3gx8: Difference between revisions
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New page: '''Unreleased structure''' The entry 3gx8 is ON HOLD Authors: Wang, Y., He, Y.X., Yu, J., Xiong, Y., Chen, Y., Zhou, C.Z. Description: Structural and biochemical characterization of ye... |
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==Structural and biochemical characterization of yeast monothiol glutaredoxin Grx5== | |||
<StructureSection load='3gx8' size='340' side='right'caption='[[3gx8]], [[Resolution|resolution]] 1.67Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3gx8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GX8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.673Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gx8 OCA], [https://pdbe.org/3gx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gx8 RCSB], [https://www.ebi.ac.uk/pdbsum/3gx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gx8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GLRX5_YEAST GLRX5_YEAST] Monothiol glutaredoxin involved in iron-sulfur biogenesis. Required for normal iron homeostasis. Protects cells against oxidative damage due to reactive oxygen species.<ref>PMID:11950925</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/3gx8_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gx8 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Chen Y]] | |||
[[Category: He YX]] | |||
[[Category: Wang Y]] | |||
[[Category: Xiong Y]] | |||
[[Category: Yu J]] | |||
[[Category: Zhou CZ]] | |||
Latest revision as of 15:45, 1 November 2023
Structural and biochemical characterization of yeast monothiol glutaredoxin Grx5
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