2rec: Difference between revisions
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New page: left|200px<br /><applet load="2rec" size="450" color="white" frame="true" align="right" spinBox="true" caption="2rec" /> '''RECA HEXAMER MODEL, ELECTRON MICROSCOPY'''<b... |
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== | ==RECA HEXAMER MODEL, ELECTRON MICROSCOPY== | ||
The RecA protein forms a hexameric ring that is similar to the core of the | <StructureSection load='2rec' size='340' side='right'caption='[[2rec]]' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2rec]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2REC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2REC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rec OCA], [https://pdbe.org/2rec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rec RCSB], [https://www.ebi.ac.uk/pdbsum/2rec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rec ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RECA_ECOLI RECA_ECOLI] Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.[HAMAP-Rule:MF_00268] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/re/2rec_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rec ConSurf]. | |||
<div style="clear:both"></div> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The RecA protein forms a hexameric ring that is similar to the core of the F1-ATPase. Several lines of evidence suggest that this hexamer may be a structural homologue of ring helicases. | |||
The RecA hexamer is a structural homologue of ring helicases.,Yu X, Egelman EH Nat Struct Biol. 1997 Feb;4(2):101-4. PMID:9033586<ref>PMID:9033586</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 2rec" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[3D structures of recombinase A|3D structures of recombinase A]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Egelman | [[Category: Egelman EH]] | ||
[[Category: Yu | [[Category: Yu X]] | ||
Latest revision as of 04:31, 8 September 2024
RECA HEXAMER MODEL, ELECTRON MICROSCOPY
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