2wh5: Difference between revisions
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New page: '''Unreleased structure''' The entry 2wh5 is ON HOLD Authors: Yue, W.W., Shafqat, N., Ugochukwu, E., Savitsky, P., Johansson, C., Salah, E., Roos, A.K., Chaikuad, A., vonDelft, F., Arro... |
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==Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA== | |||
<StructureSection load='2wh5' size='340' side='right'caption='[[2wh5]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2wh5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WH5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh5 OCA], [https://pdbe.org/2wh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wh5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACBD4_HUMAN ACBD4_HUMAN] Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wh/2wh5_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wh5 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith C]] | |||
[[Category: Bountra C]] | |||
[[Category: Chaikuad A]] | |||
[[Category: Edwards A]] | |||
[[Category: Johansson C]] | |||
[[Category: Oppermann U]] | |||
[[Category: Roos AK]] | |||
[[Category: Salah E]] | |||
[[Category: Savitsky P]] | |||
[[Category: Shafqat N]] | |||
[[Category: Ugochukwu E]] | |||
[[Category: Weigelt J]] | |||
[[Category: Yue WW]] | |||
[[Category: Von Delft F]] | |||