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'''2009 H1N1 swine flu genome and protein analysis'''
'''2009 H1N1 swine flu genome and protein analysis'''


This page was created by Michael Strong, other contributers include ...
[[User:Michael_Strong|home]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1|H1N1]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/PB2|PB2]]<font color="blue">•</font> [[User:Michael_Strong/H1N1/PB1|PB1]]<font color="blue">•</font>  [[User:Michael_Strong/H1N1/PA|PA]]  <font color="blue">•</font> [[User:Michael_Strong/H1N1/HA|HA]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NP|NP]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NA|NA]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/MP|MP]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NS|NS]]
 
 
Shown below are Protein Structural Homology Models of the PB2, PA, HA, NP, NA, MP1, MP2, NS1 and NS2 proteins from the 2009 Mexico [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=643780 A/Mexico/InDRE4487/2009] H1N1 Swine flu genome.  Sequence polymorphisms of the PB2, PB1, PA, HA, NP, NA, MP1, MP2, NS1 and NS2 proteins are also indicated, as identified by comparison of subsequently sequenced 2009 H1N1 strains from around the globe.  The "green links" next to the listed amino acids highlight the amino acid polymorphisms in the structural homology models. More detail on each protein, including Multiple Sequence Alignments of newly sequence H1N1 strains, Sequence Polymorphisms, and Related Sequence Homologs are provided on the individual protein pages (links above). 
 
Genome and protein sequences obtained from: http://www.ncbi.nlm.nih.gov/genomes/FLU/SwineFlu.html. Multiple sequence alignments of the PB2, PB1, PA, HA, NP, NA, MP, and NS proteins from 2009 H1N1 strains from Mexico, California, Texas, New York, and Canada are also provided below. 
 
== PB2 Protein Structural Homolgy Model ==
 
<applet load='MPB21.pdb' size='300' frame='true' align='center' caption='PB2 Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998206 A/Mexico/InDRE4487/2009 PB2], residues 535-742, 95% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/3cw4 3cw4]' scene ='User:Michael_Strong/H1N1/PB2/MSA/1/1' />
 
=== PB2 Sequence Polymorphisms ===
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|PB2
|I30V
|gi|229892696_A/Canada-AB/RV153
|1
|----
|PB2
|N82S
|gi|229484025_A/Mexico/InDRE448
|all others
|----
|PB2
|H151Q
|gi|237624321_A/swine/Alberta/O
|1
|----
|PB2
|D161N
|gi|227831783_A/California/06/2
|1
|----
|PB2
|V267I
|gi|229783414_A/New_York/1682/2
|1
|----
|PB2
|S324R
|gi|237624321_A/swine/Alberta/O
|1
|----
|PB2
|H432Y
|gi|237624321_A/swine/Alberta/O
|1
|----
|PB2
|L464M
|gi|229892692_A/Mexico/InDRE411
|1
|----
|PB2
|K526R
|gi|229892698_A/Canada-NS/RV153
|5
|----
|PB2
|G698D
|gi|227831783_A/California/06/2
|1
|<scene name='User:Michael_Strong/H1N1/PB2/MSA/2/1'>G698</scene>
|----
|}
 
== PB1 Sequence Polymorphisms ==
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|PB1
|L10V
|gi|229396439_A/New_York/10/200
|1
|----
|PB1
|I12T
|gi|229536040_A/Arizona/02/2009
|1
|----
|PB1
|Q48R
|gi|229783391_A/New_York/1669/2
|1
|----
|PB1
|A157V
|gi|229487525_A/Canada-NS/RV153
|2
|----
|PB1
|A370G
|gi|237624323_A/swine/Alberta/O
|1
|----
|PB1
|F466S
|gi|237624323_A/swine/Alberta/O
|1
|----
|PB1
|V587A
|gi|229487525_A/Canada-NS/RV153
|3
|----
|PB1
|N641S
|gi|229892784_A/Canada-NS/RV153
|1
|----
|PB1
|M646V
|gi|237624323_A/swine/Alberta/O
|1
|----
|PB1
|S665F
|gi|237624323_A/swine/Alberta/O
|1
|----
|PB1
|S678N
|gi|229396395_A/New_York/18/200
|1
|----
|}
 
 
 
== PA Protein Structural Homolgy Model  ==
 
<applet load='MSPA1.pdb' size='300' frame='true' align='center' caption='PA Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998223 A/Mexico/InDRE4487/2009 PA], residues 257-716, 97% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/3cm8 3cm8]' scene ='User:Michael_Strong/H1N1/PA/MSA/1/1'/>
 
=== PA Sequence Polymorphisms ===
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|PA
|S224P
|gi|227977170_A/California/07/2
|6
|----
|PA
|R269K
|gi|229484063_A/Canada-NS/RV153
|2
|<scene name='User:Michael_Strong/H1N1/PA/MSA/269/2'>269</scene>
|----
|PA
|L275I
|gi|229484065_A/Mexico/InDRE448
|all others
|<scene name='User:Michael_Strong/H1N1/PA/MSA/275/3'>275</scene>
|----
|PA
|M581L
|gi|237511889_A/Mexico/4108/200
|11
|<scene name='User:Michael_Strong/H1N1/PA/MSA/581/2'>581</scene>
|----
|PA
|L702P
|gi|237624325_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/PA/MSA/702/1'>702</scene>
|----
|}
 
== HA Protein Structural Homolgy Model  ==
 
<applet load='MSHA2.pdb' size='300' frame='true' align='center' caption='HA Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998208 A/Mexico/InDRE4487/2009 HA], residues 16-341, 83% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/3gbn 3gbn]' scene ='User:Michael_Strong/H1N1/HA/MSA/1/1'/>
 
=== HA Sequence Polymorphisms ===
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|HA
|V7I
|gi|237624327_A/swine/Alberta/O
|1
|----
|HA
|L8M
|gi|227831776_A/California/06/2
|5
|----
|HA
|A13T
|gi|229536010_A/Kansas/03/2009
|1
|----
|HA
|N48D
|gi|229536049_A/Arizona/02/2009
|1
|<scene name='User:Michael_Strong/H1N1/HA/MSA/48/1'>48</scene>
|----
|HA
|L49I
|gi|229535997_A/South_Carolina/
|2
|<scene name='User:Michael_Strong/H1N1/HA/MSA/49/1'>49</scene>
|----
|HA
|I96V
|gi|229598877_A/Ohio/07/2009
|1
|<scene name='User:Michael_Strong/H1N1/HA/MSA/96/1'>96</scene>
|----
|HA
|S100P
|gi|229535949_A/California/04/2
|5
|<scene name='User:Michael_Strong/H1N1/HA/MSA/100/1'>100</scene>
|----
|HA
|N104K
|gi|229892708_A/Canada-AB/RV153
|1
|<scene name='User:Michael_Strong/H1N1/HA/MSA/104/1'>104</scene>
|----
|HA
|V125M
|gi|229598896_A/Texas/15/2009
|2
|<scene name='User:Michael_Strong/H1N1/HA/MSA/125/1'>125</scene>
|----
|HA
|V149I
|gi|229536088_A/Indiana/09/2009
|1
|<scene name='User:Michael_Strong/H1N1/HA/MSA/149/1'>149</scene>
|----
|HA
|A214T
|gi|229535949_A/California/04/2
|2
|<scene name='User:Michael_Strong/H1N1/HA/MSA/214/1'>214</scene>
|----
|HA
|Y215N
|gi|237624327_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/HA/MSA/215/1'>215</scene>
|----
|HA
|S220T
|gi|229396494_A/Ohio/07/2009
|21
|<scene name='User:Michael_Strong/H1N1/HA/MSA/220/1'>220</scene>
|----
|HA
|F227L
|gi|229598896_A/Texas/15/2009
|1
|<scene name='User:Michael_Strong/H1N1/HA/MSA/227/1'>227</scene>
|----
|HA
|D239G
|gi|229892706A/Mexico/InDRE4114
|1
|<scene name='User:Michael_Strong/H1N1/HA/MSA/239/2'>239</scene>
|----
|HA
|D291E
|gi|229535997_A/South_Carolina/
|2
|<scene name='User:Michael_Strong/H1N1/HA/MSA/291/1'>291</scene>
|----
|HA
|N293D
|gi|229783398_A/New_York/1682/2
|1
|<scene name='User:Michael_Strong/H1N1/HA/MSA/293/2'>293</scene>
|----
|HA
|V338I
|gi|229535949_A/California/04/2
|5
|<scene name='User:Michael_Strong/H1N1/HA/MSA/338/1'>338</scene>
|----
|HA
|A351V
|gi|237624327_A/swine/Alberta/O
|1
|----
|HA
|I400V
|gi|229484027_A/Canada-NS/RV153
|3
|----
|HA
|V428I
|gi|229598877_A/Ohio/07/2009
|4
|----
|HA
|V444I
|gi|237511819_A/Mexico/4108/200
|1
|----
|HA
|I527F
|gi|229892706A/Mexico/InDRE4114
|1
|----
|}
 
<scene name='User:Michael_Strong/H1N1/HA/MSA/All/1'>All Polymorphisms</scene>
 
== NP Protein Structural Homolgy Model  ==
 
<applet load='MSNP1.pdb' size='300' frame='true' align='center' caption='NP Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998217 A/Mexico/InDRE4487/2009 NP], residues 28-502, 94% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/2q06 2q06]' scene ='User:Michael_Strong/H1N1/NP/MSA/1/1'/>
 
=== NP Sequence Polymorphisms ===
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|NP
|G22D
|gi|229598884_A/Texas/15/2009
|1
|----
|NP
|V35A
|gi|237624329_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/35/1'>35</scene>
|----
|NP
|S90N
|gi|229536012_A/Arizona/01/2009
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/90/1'>90</scene>
|----
|NP
|V106I
|gi|229892748_A/Canada-ON/RV152
|28
|<scene name='User:Michael_Strong/H1N1/NP/MSA/106/1'>106</scene>
|----
|NP
|Q128L
|gi|227977162_A/California/07/2
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/128/1'>128</scene>
|----
|NP
|L139I
|gi|229783384_A/New_York/1669/2
|2
|<scene name='User:Michael_Strong/H1N1/NP/MSA/139/1'>139</scene>
|----
|NP
|E198K
|gi|237624329_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/198/1'>198</scene>
|----
|NP
|N208D
|gi|237624329_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/208/1'>208</scene>
|----
|NP
|V223I
|gi|229536102_A/Nebraska/02/200
|2
|<scene name='User:Michael_Strong/H1N1/NP/MSA/223/1'>223</scene>
|----
|NP
|M228T
|gi|237624329_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/228/1'>228</scene>
|----
|NP
|A257T
|gi|229396492_A/Ohio/07/2009
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/257/1'>257</scene>
|----
|NP
|V349I
|gi|229536131_A/Colorado/03/200
|2
|<scene name='User:Michael_Strong/H1N1/NP/MSA/349/1'>349</scene>
|----
|NP
|V358M
|gi|229598873_A/Ohio/07/2009
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/358/1'>358</scene>
|----
|NP
|V369I
|gi|229536077_A/Indiana/09/2009
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/369/1'>369</scene>
|----
|NP
|T379I
|gi|229536102_A/Nebraska/02/200
|18
|<scene name='User:Michael_Strong/H1N1/NP/MSA/379/1'>379</scene>
|----
|NP
|T379V
|gi|229892752_A/Canada-NS/RV153
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/379/1'>379</scene>
|----
|NP
|D381N
|gi|229396423_A/California/08/2
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/381/1'>381</scene>
|----
|NP
|D381Y
|gi|237624329_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/381/1'>381</scene>
|----
|NP
|T402A
|gi|237511901_A/Mexico/4516/200
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/402/1'>402</scene>
|----
|NP
|S456N
|gi|229536077_A/Indiana/09/2009
|1
|<scene name='User:Michael_Strong/H1N1/NP/MSA/456/1'>456</scene>
|----
|}
 
<scene name='User:Michael_Strong/H1N1/NP/MSA/All/1'>All Polymorphisms</scene>
 
== NA Protein Structural Homolgy Model  ==
 
<applet load='MSNA1.pdb' size='300' frame='true' align='center' caption='NA Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998214 A/Mexico/InDRE4487/2009 NA], residues 83-467, 89% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/3b7e 3b7e]' scene ='User:Michael_Strong/H1N1/NA/MSA/1/1'/>
 
=== NA Sequence Polymorphisms ===
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|NA
|H36R
|gi|229892732_A/Mexico/InDRE411
|1
|----
|NA
|E57K
|gi|229536081_A/Indiana/09/2009
|1
|----
|NA
|V83M
|gi|229536111_A/Michigan/02/200
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/83/1'>83</scene>
|----
|NA
|S95G
|gi|228017756_A/California/06/2
|5
|<scene name='User:Michael_Strong/H1N1/NA/MSA/95/2'>95</scene>
|----
|NA
|G96E
|gi|237624331_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/96/2'>96</scene>
|----
|NA
|Y100H
|gi|237624331_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/100/1'>100</scene>
|----
|NA
|V106I
|gi|228481034_A/Auckland/3/2009
|30
|<scene name='User:Michael_Strong/H1N1/NA/MSA/106/1'>106</scene>
|----
|NA
|I108V
|gi|228860931_A/Netherlands/602
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/108/1'>108</scene>
|----
|NA
|P120S
|gi|229892684_A/Catalonia/P48/2
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/120/1'>120</scene>
|----
|NA
|S123L
|gi|237624331_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/123/1'>123</scene>
|----
|NA
|V241I
|gi|229535806_A/Texas/09/2009
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/241/1'>241</scene>
|----
|NA
|N248D
|gi|229396353_A/New_York/12/200
|30
|<scene name='User:Michael_Strong/H1N1/NA/MSA/248/1'>248</scene>
|----
|NA
|N307T
|gi|228481034_A/Auckland/3/2009
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/307/1'>307</scene>
|----
|NA
|S319R
|gi|229892682_A/Korea/01/2009
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/319/1'>319</scene>
|----
|NA
|S334C
|gi|237624331_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NA/MSA/334/1'>334</scene>
|----
|}
<scene name='User:Michael_Strong/H1N1/NA/MSA/All/1'>All Polymorphisms</scene>
 
==MP1 Protein Structural Homolgy Model  ==
 
<applet load='MMP21.pdb' size='300' frame='true' align='center' caption='MP2 Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998211 A/Mexico/InDRE4487/2009 MP1], residues 23-60, 82% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/2rlf 2rlf]' scene ='User:Michael_Strong/H1N1/MP/1/2'/>
 
===MP1 Sequence Polymorphisms===
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|MP1
|L3P
|gi|227831763_A/California/05/2
|1
|<scene name='User:Michael_Strong/H1N1/MP/3/2'>3</scene>
|----
|MP1
|H222R
|gi|237624333_A/swine/Alberta/O
|1
|----
|MP1
|A227T
|gi|229484039_A/Canada-ON/RV152
|2
|----
|}
 
==MP2 Protein Structural Homolgy Model ==
 
<applet load='MMP21.pdb' size='300' frame='true' align='center' caption='MP2 Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998211 A/Mexico/InDRE4487/2009 MP2], residues 23-60, 82% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/2rlf 2rlf]' scene ='User:Michael_Strong/H1N1/MP2/MSA/1/1'/>
 
===MP2 Sequence Polymorphisms ===
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|MP2
|L3P
|gi|227831764_A/California/05/2
|1
|----
|MP2
|Y52H
|gi|229609551_A/Stockholm/28/20
|1
|<scene name='User:Michael_Strong/H1N1/MP2/MSA/52/1'>52</scene>
|----
|MP2
|T65M
|gi|229536073_A/Texas/07/2009
|1
|----
|MP2
|S82N
|gi|237511788_A/Mexico/4108/200
|1
|----
|}
 
== NS1 Protein Structural Homolgy Model  ==
 
<applet load='MNS21.pdb' size='300' frame='true' align='center' caption='NS1 Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998220 A/Mexico/InDRE4487/2009 NS1], residues 5-202, 84% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/3f5t 3f5t]' scene ='User:Michael_Strong/H1N1/NS1/MSA/1/1'/>
 
=== NS1 Sequence Polymorphisms ===
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|NS1
|D12E
|gi|229536107_A/Nebraska/02/200
|1
|<scene name='User:Michael_Strong/H1N1/NS1/MSA/12/1'>12</scene>
|----
|NS1
|F32L
|gi|229535811_A/Texas/09/2009
|1
|<scene name='User:Michael_Strong/H1N1/NS1/MSA/32/1'>32</scene>
|----
|NS1
|G45R
|gi|229598886_A/Texas/15/2009
|1
|<scene name='User:Michael_Strong/H1N1/NS1/MSA/45/1'>45</scene>
|----
|NS1
|R88C
|gi|229536033_A/Minnesota/02/20
|1
|<scene name='User:Michael_Strong/H1N1/NS1/MSA/88/1'>88</scene>
|----
|NS1
|E97G
|gi|229892754_A/Canada-NS/RV153
|1
|<scene name='User:Michael_Strong/H1N1/NS1/MSA/97/1'>97</scene>
|----
|NS1
|M104T
|gi|237624336_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NS1/MSA/104/1'>104</scene>
|----
|NS1
|I123V
|gi|229892764_A/Canada-AB/RV153
|15
|<scene name='User:Michael_Strong/H1N1/NS1/MSA/123/1'>123</scene>
|----
|NS1
|F134I
|gi|237624336_A/swine/Alberta/O
|1
|<scene name='User:Michael_Strong/H1N1/NS1/MSA/134/1'>134</scene>
|----
|}
 
<scene name='User:Michael_Strong/H1N1/NS1/MSA/All/2'>All Polymorphisms</scene>
 
== NS2 Protein Structural Homolgy Model ==
 
<applet load='MNS22.pdb' size='300' frame='true' align='center' caption='NS2 Homology Model, Mexico Strain, [http://www.ncbi.nlm.nih.gov/nuccore/FJ998220 A/Mexico/InDRE4487/2009 NS2], residues 64-116, 94% sequence identity to pdp template [http://proteopedia.org/wiki/index.php/1pd3 1pd3]' scene ='User:Michael_Strong/H1N1/NS2/MSA/1/1'/>
 
=== NS2 Sequence Polymorphisms ===
 
{| class="wikitable"
|Protein
|Polymorphism
|Strain with Polymorphism
|Number of Strains with Polymorphism
|----
|NS2
|E63K
|gi|229783374_A/Korea/01/2009
|1
|----
|NS2
|E67K
|gi|229598887_A/Texas/15/2009
|1
|<scene name='User:Michael_Strong/H1N1/NS2/MSA/67/1'>67</scene>
|----
|NS2
|A89E
|gi|228017754_A/California/06/2
|3
|<scene name='User:Michael_Strong/H1N1/NS2/MSA/89/1'>89</scene>
|----
|NS2
|A115T
|gi|229892755_A/Canada-NS/RV153
|1
|<scene name='User:Michael_Strong/H1N1/NS2/MSA/115/1'>115</scene>
|----
|}
 
<scene name='User:Michael_Strong/H1N1/NS2/MSA/All/1'>All Polymorphisms</scene>
 
 
==Multiple Sequence Alignment of 5 H1N1 Strains==
===multiple sequence alignment of PB2===
 
CLUSTAL 2.0.10 multiple sequence alignment
 
--------------------
'''PB2'''
<PRE>CLUSTAL 2.0.10 =
multiple sequence alignment of PB2
 
A/California/04/2009        MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWM 50
A/New_York/18/2009          MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWM 50
A/Canada-ON/RV1527/2009      MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWM 50
A/Texas/09/2009              MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWM 50
A/Mexico/InDRE4487/2009      MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWM 50
                            **************************************************
 
A/California/04/2009        MAMRYPITADKRIMDMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWN 100
A/New_York/18/2009          MAMRYPITADKRIMDMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWN 100
A/Canada-ON/RV1527/2009      MAMRYPITADKRIMDMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWN 100
A/Texas/09/2009              MAMRYPITADKRIMDMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWN 100
A/Mexico/InDRE4487/2009      MAMRYPITADKRIMDMIPERNEQGQTLWSKTSDAGSDRVMVSPLAVTWWN 100
                            *******************************.******************
 
A/California/04/2009        RNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDTNPG 150
A/New_York/18/2009          RNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDTNPG 150
A/Canada-ON/RV1527/2009      RNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDTNPG 150
A/Texas/09/2009              RNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDTNPG 150
A/Mexico/InDRE4487/2009      RNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDTNPG 150
                            **************************************************
 
A/California/04/2009        HADLSAKEAQDVIMEVVFPNEVGARILTSESQLAITKEKKEELQDCKIAP 200
A/New_York/18/2009          HADLSAKEAQDVIMEVVFPNEVGARILTSESQLAITKEKKEELQDCKIAP 200
A/Canada-ON/RV1527/2009      HADLSAKEAQDVIMEVVFPNEVGARILTSESQLAITKEKKEELQDCKIAP 200
A/Texas/09/2009              HADLSAKEAQDVIMEVVFPNEVGARILTSESQLAITKEKKEELQDCKIAP 200
A/Mexico/InDRE4487/2009      HADLSAKEAQDVIMEVVFPNEVGARILTSESQLAITKEKKEELQDCKIAP 200
                            **************************************************
 
A/California/04/2009        LMVAYMLERELVRKTRFLPVAGGTGSVYIEVLHLTQGTCWEQMYTPGGEV 250
A/New_York/18/2009          LMVAYMLERELVRKTRFLPVAGGTGSVYIEVLHLTQGTCWEQMYTPGGEV 250
A/Canada-ON/RV1527/2009      LMVAYMLERELVRKTRFLPVAGGTGSVYIEVLHLTQGTCWEQMYTPGGEV 250
A/Texas/09/2009              LMVAYMLERELVRKTRFLPVAGGTGSVYIEVLHLTQGTCWEQMYTPGGEV 250
A/Mexico/InDRE4487/2009      LMVAYMLERELVRKTRFLPVAGGTGSVYIEVLHLTQGTCWEQMYTPGGEV 250
                            **************************************************
 
A/California/04/2009        RNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGVRMVDILRQ 300
A/New_York/18/2009          RNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGVRMVDILRQ 300
A/Canada-ON/RV1527/2009      RNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGVRMVDILRQ 300
A/Texas/09/2009              RNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGVRMVDILRQ 300
A/Mexico/InDRE4487/2009      RNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGVRMVDILRQ 300
                            **************************************************
 
A/California/04/2009        NPTEEQAVDICKAAIGLRISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQ 350
A/New_York/18/2009          NPTEEQAVDICKAAIGLRISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQ 350
A/Canada-ON/RV1527/2009      NPTEEQAVDICKAAIGLRISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQ 350
A/Texas/09/2009              NPTEEQAVDICKAAIGLRISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQ 350
A/Mexico/InDRE4487/2009      NPTEEQAVDICKAAIGLRISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQ 350
                            **************************************************
 
A/California/04/2009        TLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIV 400
A/New_York/18/2009          TLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIV 400
A/Canada-ON/RV1527/2009      TLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIV 400
A/Texas/09/2009              TLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIV 400
A/Mexico/InDRE4487/2009      TLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIV 400
                            **************************************************
 
A/California/04/2009        AMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWG 450
A/New_York/18/2009          AMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWG 450
A/Canada-ON/RV1527/2009      AMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWG 450
A/Texas/09/2009              AMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWG 450
A/Mexico/InDRE4487/2009      AMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWG 450
                            **************************************************
 
A/California/04/2009        IESIDNVMGMIGILPDMTPSTEMSLRGIRVSKMGVDEYSSTERVVVSIDR 500
A/New_York/18/2009          IESIDNVMGMIGILPDMTPSTEMSLRGIRVSKMGVDEYSSTERVVVSIDR 500
A/Canada-ON/RV1527/2009      IESIDNVMGMIGILPDMTPSTEMSLRGIRVSKMGVDEYSSTERVVVSIDR 500
A/Texas/09/2009              IESIDNVMGMIGILPDMTPSTEMSLRGIRVSKMGVDEYSSTERVVVSIDR 500
A/Mexico/InDRE4487/2009      IESIDNVMGMIGILPDMTPSTEMSLRGIRVSKMGVDEYSSTERVVVSIDR 500
                            **************************************************
 
A/California/04/2009        FLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTY 550
A/New_York/18/2009          FLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTY 550
A/Canada-ON/RV1527/2009      FLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTY 550
A/Texas/09/2009              FLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTY 550
A/Mexico/InDRE4487/2009      FLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTY 550
                            **************************************************
 
A/California/04/2009        QWIIRNWEIVKIQWSQDPTMLYNKMEFEPFQSLVPKATRSRYSGFVRTLF 600
A/New_York/18/2009          QWIIRNWEIVKIQWSQDPTMLYNKMEFEPFQSLVPKATRSRYSGFVRTLF 600
A/Canada-ON/RV1527/2009      QWIIRNWEIVKIQWSQDPTMLYNKMEFEPFQSLVPKATRSRYSGFVRTLF 600
A/Texas/09/2009              QWIIRNWEIVKIQWSQDPTMLYNKMEFEPFQSLVPKATRSRYSGFVRTLF 600
A/Mexico/InDRE4487/2009      QWIIRNWEIVKIQWSQDPTMLYNKMEFEPFQSLVPKATRSRYSGFVRTLF 600
                            **************************************************
 
A/California/04/2009        QQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGLRILVR 650
A/New_York/18/2009          QQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGLRILVR 650
A/Canada-ON/RV1527/2009      QQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGLRILVR 650
A/Texas/09/2009              QQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGLRILVR 650
A/Mexico/InDRE4487/2009      QQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGLRILVR 650
                            **************************************************
 
A/California/04/2009        GNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTSGVESAVLRGFLILGKE 700
A/New_York/18/2009          GNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTSGVESAVLRGFLILGKE 700
A/Canada-ON/RV1527/2009      GNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTSGVESAVLRGFLILGKE 700
A/Texas/09/2009              GNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTSGVESAVLRGFLILGKE 700
A/Mexico/InDRE4487/2009      GNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTSGVESAVLRGFLILGKE 700
                            **************************************************
 
A/California/04/2009        DKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTA 750
A/New_York/18/2009          DKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTA 750
A/Canada-ON/RV1527/2009      DKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTA 750
A/Texas/09/2009              DKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTA 750
A/Mexico/InDRE4487/2009      DKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTA 750
                            **************************************************
 
A/California/04/2009        TKRIRMAIN 759
A/New_York/18/2009          TKRIRMAIN 759
A/Canada-ON/RV1527/2009      TKRIRMAIN 759
A/Texas/09/2009              TKRIRMAIN 759
A/Mexico/InDRE4487/2009      TKRIRMAIN 759
                            *********
</PRE><SPAN class=3Dpsmall>
 
--------------------
===multiple sequence alignment of PB1===
'''PB1'''
<PRE>CLUSTAL 2.0.10 =
multiple sequence alignment of PB1
 
A/Canada-ON/RV1527/2009      MDVNPTLLFLKIPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYS 50
A/Texas/09/2009              MDVNPTLLFLKIPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYS 50
A/Mexico/InDRE4487/2009      MDVNPTLLFLKIPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYS 50
A/California/04/2009        MDVNPTLLFLKIPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYS 50
A/New_York/18/2009          MDVNPTLLFLKIPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYS 50
                            **************************************************
 
A/Canada-ON/RV1527/2009      EKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHP 100
A/Texas/09/2009              EKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHP 100
A/Mexico/InDRE4487/2009      EKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHP 100
A/California/04/2009        EKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHP 100
A/New_York/18/2009          EKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHP 100
                            **************************************************
 
A/Canada-ON/RV1527/2009      GIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF 150
A/Texas/09/2009              GIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF 150
A/Mexico/InDRE4487/2009      GIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF 150
A/California/04/2009        GIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF 150
A/New_York/18/2009          GIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF 150
                            **************************************************
 
A/Canada-ON/RV1527/2009      RSNGLTANESGRLIDFLKDVMESMNKEEIEITTHFQRKRRVRDNMTKKMV 200
A/Texas/09/2009              RSNGLTANESGRLIDFLKDVMESMNKEEIEITTHFQRKRRVRDNMTKKMV 200
A/Mexico/InDRE4487/2009      RSNGLTANESGRLIDFLKDVMESMNKEEIEITTHFQRKRRVRDNMTKKMV 200
A/California/04/2009        RSNGLTANESGRLIDFLKDVMESMNKEEIEITTHFQRKRRVRDNMTKKMV 200
A/New_York/18/2009          RSNGLTANESGRLIDFLKDVMESMNKEEIEITTHFQRKRRVRDNMTKKMV 200
                            **************************************************
 
A/Canada-ON/RV1527/2009      TQRTIGKKKQRLNKRGYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRG 250
A/Texas/09/2009              TQRTIGKKKQRLNKRGYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRG 250
A/Mexico/InDRE4487/2009      TQRTIGKKKQRLNKRGYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRG 250
A/California/04/2009        TQRTIGKKKQRLNKRGYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRG 250
A/New_York/18/2009          TQRTIGKKKQRLNKRGYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRG 250
                            **************************************************
 
A/Canada-ON/RV1527/2009      FVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISF 300
A/Texas/09/2009              FVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISF 300
A/Mexico/InDRE4487/2009      FVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISF 300
A/California/04/2009        FVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISF 300
A/New_York/18/2009          FVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISF 300
                            **************************************************
 
A/Canada-ON/RV1527/2009      TITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNILSMAPIMFSNKMAR 350
A/Texas/09/2009              TITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNILSMAPIMFSNKMAR 350
A/Mexico/InDRE4487/2009      TITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNILSMAPIMFSNKMAR 350
A/California/04/2009        TITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNILSMAPIMFSNKMAR 350
A/New_York/18/2009          TITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNILSMAPIMFSNKMAR 350
                            **************************************************
 
A/Canada-ON/RV1527/2009      LGKGYMFESKRMKIRTQIPAEMLASIDLKYFNESTKKKIEKIRPLLIDGT 400
A/Texas/09/2009              LGKGYMFESKRMKIRTQIPAEMLASIDLKYFNESTKKKIEKIRPLLIDGT 400
A/Mexico/InDRE4487/2009      LGKGYMFESKRMKIRTQIPAEMLASIDLKYFNESTKKKIEKIRPLLIDGT 400
A/California/04/2009        LGKGYMFESKRMKIRTQIPAEMLASIDLKYFNESTKKKIEKIRPLLIDGT 400
A/New_York/18/2009          LGKGYMFESKRMKIRTQIPAEMLASIDLKYFNESTKKKIEKIRPLLIDGT 400
                            **************************************************
 
A/Canada-ON/RV1527/2009      ASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTIYWWDGLQSSDDFALI 450
A/Texas/09/2009              ASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTIYWWDGLQSSDDFALI 450
A/Mexico/InDRE4487/2009      ASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTIYWWDGLQSSDDFALI 450
A/California/04/2009        ASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTIYWWDGLQSSDDFALI 450
A/New_York/18/2009          ASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTIYWWDGLQSSDDFALI 450
                            **************************************************
 
A/Canada-ON/RV1527/2009      VNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINKTGTFEFTSFFYRYG 500
A/Texas/09/2009              VNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINKTGTFEFTSFFYRYG 500
A/Mexico/InDRE4487/2009      VNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINKTGTFEFTSFFYRYG 500
A/California/04/2009        VNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINKTGTFEFTSFFYRYG 500
A/New_York/18/2009          VNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINKTGTFEFTSFFYRYG 500
                            **************************************************
 
A/Canada-ON/RV1527/2009      FVANFSMELPSFGVSGVNESADMSIGVTVIKNNMINNDLGPATAQMALQL 550
A/Texas/09/2009              FVANFSMELPSFGVSGVNESADMSIGVTVIKNNMINNDLGPATAQMALQL 550
A/Mexico/InDRE4487/2009      FVANFSMELPSFGVSGVNESADMSIGVTVIKNNMINNDLGPATAQMALQL 550
A/California/04/2009        FVANFSMELPSFGVSGVNESADMSIGVTVIKNNMINNDLGPATAQMALQL 550
A/New_York/18/2009          FVANFSMELPSFGVSGVNESADMSIGVTVIKNNMINNDLGPATAQMALQL 550
                            **************************************************
 
A/Canada-ON/RV1527/2009      FIKDYRYTYRCHRGDTQIQTRRSFELKKLWDQTQSKVGLLVSDGGPNLYN 600
A/Texas/09/2009              FIKDYRYTYRCHRGDTQIQTRRSFELKKLWDQTQSKVGLLVSDGGPNLYN 600
A/Mexico/InDRE4487/2009      FIKDYRYTYRCHRGDTQIQTRRSFELKKLWDQTQSKVGLLVSDGGPNLYN 600
A/California/04/2009        FIKDYRYTYRCHRGDTQIQTRRSFELKKLWDQTQSKVGLLVSDGGPNLYN 600
A/New_York/18/2009          FIKDYRYTYRCHRGDTQIQTRRSFELKKLWDQTQSKVGLLVSDGGPNLYN 600
                            **************************************************
 
A/Canada-ON/RV1527/2009      IRNLHIPEVCLKWELMDDDYRGRLCNPLNPFVSHKEIDSVNNAVVMPAHG 650
A/Texas/09/2009              IRNLHIPEVCLKWELMDDDYRGRLCNPLNPFVSHKEIDSVNNAVVMPAHG 650
A/Mexico/InDRE4487/2009      IRNLHIPEVCLKWELMDDDYRGRLCNPLNPFVSHKEIDSVNNAVVMPAHG 650
A/California/04/2009        IRNLHIPEVCLKWELMDDDYRGRLCNPLNPFVSHKEIDSVNNAVVMPAHG 650
A/New_York/18/2009          IRNLHIPEVCLKWELMDDDYRGRLCNPLNPFVSHKEIDSVNNAVVMPAHG 650
                            **************************************************
 
A/Canada-ON/RV1527/2009      PAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFF 700
A/Texas/09/2009              PAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFF 700
A/Mexico/InDRE4487/2009      PAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFF 700
A/California/04/2009        PAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFF 700
A/New_York/18/2009          PAKSMEYDAVATTHSWIPKRNRSILNTNQRGILEDEQMYQKCCNLFEKFF 700
                            ***************************.**********************
 
A/Canada-ON/RV1527/2009      PSSSYRRPVGISSMVEAMVSRARIDARVDFESGRIKKEEFSEIMKICSTI 750
A/Texas/09/2009              PSSSYRRPVGISSMVEAMVSRARIDARVDFESGRIKKEEFSEIMKICSTI 750
A/Mexico/InDRE4487/2009      PSSSYRRPVGISSMVEAMVSRARIDARVDFESGRIKKEEFSEIMKICSTI 750
A/California/04/2009        PSSSYRRPVGISSMVEAMVSRARIDARVDFESGRIKKEEFSEIMKICSTI 750
A/New_York/18/2009          PSSSYRRPVGISSMVEAMVSRARIDARVDFESGRIKKEEFSEIMKICSTI 750
                            **************************************************
 
A/Canada-ON/RV1527/2009      EELRRQK 757
A/Texas/09/2009              EELRRQK 757
A/Mexico/InDRE4487/2009      EELRRQK 757
A/California/04/2009        EELRRQK 757
A/New_York/18/2009          EELRRQK 757
                            *******
</PRE><SPAN class=3Dpsmall>
 
 
--------------------
===multiple sequence alignment of PA===
'''PA'''
<PRE>CLUSTAL 2.0.10 =
multiple sequence alignment of PA
 
A/Canada-ON/RV1527/2009      MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD 50
A/Texas/09/2009              MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD 50
A/Mexico/InDRE4487/2009      MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD 50
A/New_York/18/2009          MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD 50
A/California/04/2009        MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD 50
                            **************************************************
 
A/Canada-ON/RV1527/2009      FHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGV 100
A/Texas/09/2009              FHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGV 100
A/Mexico/InDRE4487/2009      FHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGV 100
A/New_York/18/2009          FHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGV 100
A/California/04/2009        FHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGV 100
                            **************************************************
 
A/Canada-ON/RV1527/2009      EKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSF 150
A/Texas/09/2009              EKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSF 150
A/Mexico/InDRE4487/2009      EKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSF 150
A/New_York/18/2009          EKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSF 150
A/California/04/2009        EKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSF 150
                            **************************************************
 
A/Canada-ON/RV1527/2009      TGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERGEET 200
A/Texas/09/2009              TGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERGEET 200
A/Mexico/InDRE4487/2009      TGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERGEET 200
A/New_York/18/2009          TGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERGEET 200
A/California/04/2009        TGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERGEET 200
                            **************************************************
 
A/Canada-ON/RV1527/2009      IEEKFEITGTMRKLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMS 250
A/Texas/09/2009              IEEKFEITGTMRKLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMS 250
A/Mexico/InDRE4487/2009      IEEKFEITGTMRKLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMS 250
A/New_York/18/2009          IEEKFEITGTMRKLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMS 250
A/California/04/2009        IEEKFEITGTMRKLADQSLPPNFPSLENFRAYVDGFEPNGCIEGKLSQMS 250
                            ***********************.**************************
 
A/Canada-ON/RV1527/2009      KEVNAKIEPFLRTTPRPLRLPDGPLCHQRSKFLLMDALKLSIEDPSHEGE 300
A/Texas/09/2009              KEVNAKIEPFLRTTPRPLRLPDGPLCHQRSKFLLMDALKLSIEDPSHEGE 300
A/Mexico/InDRE4487/2009      KEVNAKIEPFLRTTPRPLRLPDGPICHQRSKFLLMDALKLSIEDPSHEGE 300
A/New_York/18/2009          KEVNAKIEPFLRTTPRPLRLPDGPLCHQRSKFLLMDALKLSIEDPSHEGE 300
A/California/04/2009        KEVNAKIEPFLRTTPRPLRLPDGPLCHQRSKFLLMDALKLSIEDPSHEGE 300
                            ************************:*************************
 
A/Canada-ON/RV1527/2009      GIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLMAWKQVLAELQDIEN 350
A/Texas/09/2009              GIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLMAWKQVLAELQDIEN 350
A/Mexico/InDRE4487/2009      GIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLMAWKQVLAELQDIEN 350
A/New_York/18/2009          GIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLMAWKQVLAELQDIEN 350
A/California/04/2009        GIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLMAWKQVLAELQDIEN 350
                            **************************************************
 
A/Canada-ON/RV1527/2009      EEKIPRTKNMKRTSQLKWALGENMAPEKVDFDDCKDVGDLKQYDSDEPEP 400
A/Texas/09/2009              EEKIPRTKNMKRTSQLKWALGENMAPEKVDFDDCKDVGDLKQYDSDEPEP 400
A/Mexico/InDRE4487/2009      EEKIPRTKNMKRTSQLKWALGENMAPEKVDFDDCKDVGDLKQYDSDEPEP 400
A/New_York/18/2009          EEKIPRTKNMKRTSQLKWALGENMAPEKVDFDDCKDVGDLKQYDSDEPEP 400
A/California/04/2009        EEKIPRTKNMKRTSQLKWALGENMAPEKVDFDDCKDVGDLKQYDSDEPEP 400
                            **************************************************
 
A/Canada-ON/RV1527/2009      RSLASWVQNEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEV 450
A/Texas/09/2009              RSLASWVQNEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEV 450
A/Mexico/InDRE4487/2009      RSLASWVQNEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEV 450
A/New_York/18/2009          RSLASWVQNEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEV 450
A/California/04/2009        RSLASWVQNEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEV 450
                            **************************************************
 
A/Canada-ON/RV1527/2009      SHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNL 500
A/Texas/09/2009              SHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNL 500
A/Mexico/InDRE4487/2009      SHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNL 500
A/New_York/18/2009          SHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNL 500
A/California/04/2009        SHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNL 500
                            **************************************************
 
A/Canada-ON/RV1527/2009      YGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLL 550
A/Texas/09/2009              YGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLL 550
A/Mexico/InDRE4487/2009      YGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLL 550
A/New_York/18/2009          YGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLL 550
A/California/04/2009        YGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLL 550
                            **************************************************
 
A/Canada-ON/RV1527/2009      RTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAES 600
A/Texas/09/2009              RTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAES 600
A/Mexico/InDRE4487/2009      RTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAES 600
A/New_York/18/2009          RTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAES 600
A/California/04/2009        RTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAES 600
                            **************************************************
 
A/Canada-ON/RV1527/2009      SVKEKDMTKEFFENKSETWPIGESPRGVEEGSIGKVCRTLLAKSVFNSLY 650
A/Texas/09/2009              SVKEKDMTKEFFENKSETWPIGESPRGVEEGSIGKVCRTLLAKSVFNSLY 650
A/Mexico/InDRE4487/2009      SVKEKDMTKEFFENKSETWPIGESPRGVEEGSIGKVCRTLLAKSVFNSLY 650
A/New_York/18/2009          SVKEKDMTKEFFENKSETWPIGESPRGVEEGSIGKVCRTLLAKSVFNSLY 650
A/California/04/2009        SVKEKDMTKEFFENKSETWPIGESPRGVEEGSIGKVCRTLLAKSVFNSLY 650
                            **************************************************
 
A/Canada-ON/RV1527/2009      ASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWV 700
A/Texas/09/2009              ASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWV 700
A/Mexico/InDRE4487/2009      ASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWV 700
A/New_York/18/2009          ASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWV 700
A/California/04/2009        ASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWV 700
                            **************************************************
 
A/Canada-ON/RV1527/2009      LLNASWFNSFLTHALK 716
A/Texas/09/2009              LLNASWFNSFLTHALK 716
A/Mexico/InDRE4487/2009      LLNASWFNSFLTHALK 716
A/New_York/18/2009          LLNASWFNSFLTHALK 716
A/California/04/2009        LLNASWFNSFLTHALK 716
                            ****************
 
</PRE><SPAN class=3Dpsmall>
 
 
 
--------------------
===multiple sequence alignment of HA===
'''HA'''
<PRE>CLUSTAL 2.0.10 =
multiple sequence alignment of HA
 
A/Texas/04/2009              MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVTHSVNLL 50
A/Mexico/InDRE4487/2009      MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVTHSVNLL 50
A/New_York/18/2009          MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVTHSVNLL 50
A/Canada-ON/RV1527/2009      MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVTHSVNLL 50
A/California/04/2009        MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVTHSVNLL 50
                            **************************************************
 
A/Texas/04/2009              EDKHNGKLCKLRGVAPLHLGKCNIAGWILGNPECESLSTASSWSYIVETS 100
A/Mexico/InDRE4487/2009      EDKHNGKLCKLRGVAPLHLGKCNIAGWILGNPECESLSTASSWSYIVETS 100
A/New_York/18/2009          EDKHNGKLCKLRGVAPLHLGKCNIAGWILGNPECESLSTASSWSYIVETS 100
A/Canada-ON/RV1527/2009      EDKHNGKLCKLRGVAPLHLGKCNIAGWILGNPECESLSTASSWSYIVETS 100
A/California/04/2009        EDKHNGKLCKLRGVAPLHLGKCNIAGWILGNPECESLSTASSWSYIVETP 100
                            *************************************************.
 
A/Texas/04/2009              SSDNGTCYPGDFIDYEELREQLSSVSSFERFEIFPKTSSWPNHDSNKGVT 150
A/Mexico/InDRE4487/2009      SSDNGTCYPGDFIDYEELREQLSSVSSFERFEIFPKTSSWPNHDSNKGVT 150
A/New_York/18/2009          SSDNGTCYPGDFIDYEELREQLSSVSSFERFEIFPKTSSWPNHDSNKGVT 150
A/Canada-ON/RV1527/2009      SSDNGTCYPGDFIDYEELREQLSSVSSFERFEIFPKTSSWPNHDSNKGVT 150
A/California/04/2009        SSDNGTCYPGDFIDYEELREQLSSVSSFERFEIFPKTSSWPNHDSNKGVT 150
                            **************************************************
 
A/Texas/04/2009              AACPHAGAKSFYKNLIWLVKKGNSYPKLSKSYINDKGKEVLVLWGIHHPS 200
A/Mexico/InDRE4487/2009      AACPHAGAKSFYKNLIWLVKKGNSYPKLSKSYINDKGKEVLVLWGIHHPS 200
A/New_York/18/2009          AACPHAGAKSFYKNLIWLVKKGNSYPKLSKSYINDKGKEVLVLWGIHHPS 200
A/Canada-ON/RV1527/2009      AACPHAGAKSFYKNLIWLVKKGNSYPKLSKSYINDKGKEVLVLWGIHHPS 200
A/California/04/2009        AACPHAGAKSFYKNLIWLVKKGNSYPKLSKSYINDKGKEVLVLWGIHHPS 200
                            **************************************************
 
A/Texas/04/2009              TSADQQSLYQNADAYVFVGSSRYSKKFKPEIAIRPKVRDQEGRMNYYWTL 250
A/Mexico/InDRE4487/2009      TSADQQSLYQNADAYVFVGSSRYSKKFKPEIAIRPKVRDQEGRMNYYWTL 250
A/New_York/18/2009          TSADQQSLYQNADAYVFVGTSRYSKKFKPEIAIRPKVRDQEGRMNYYWTL 250
A/Canada-ON/RV1527/2009      TSADQQSLYQNADAYVFVGTSRYSKKFKPEIAIRPKVRDQEGRMNYYWTL 250
A/California/04/2009        TSADQQSLYQNADTYVFVGSSRYSKKFKPEIAIRPKVRDQEGRMNYYWTL 250
                            *************:*****:******************************
 
A/Texas/04/2009              VEPGDKITFEATGNLVVPRYAFAMERNAGSGIIISDTPVHDCNTTCQTPK 300
A/Mexico/InDRE4487/2009      VEPGDKITFEATGNLVVPRYAFAMERNAGSGIIISDTPVHDCNTTCQTPK 300
A/New_York/18/2009          VEPGDKITFEATGNLVVPRYAFAMERNAGSGIIISDTPVHDCNTTCQTPK 300
A/Canada-ON/RV1527/2009      VEPGDKITFEATGNLVVPRYAFAMERNAGSGIIISDTPVHDCNTTCQTPK 300
A/California/04/2009        VEPGDKITFEATGNLVVPRYAFAMERNAGSGIIISDTPVHDCNTTCQTPK 300
                            **************************************************
 
A/Texas/04/2009              GAINTSLPFQNIHPITIGKCPKYVKSTKLRLATGLRNVPSIQSRGLFGAI 350
A/Mexico/InDRE4487/2009      GAINTSLPFQNIHPITIGKCPKYVKSTKLRLATGLRNVPSIQSRGLFGAI 350
A/New_York/18/2009          GAINTSLPFQNIHPITIGKCPKYVKSTKLRLATGLRNVPSIQSRGLFGAI 350
A/Canada-ON/RV1527/2009      GAINTSLPFQNIHPITIGKCPKYVKSTKLRLATGLRNVPSIQSRGLFGAI 350
A/California/04/2009        GAINTSLPFQNIHPITIGKCPKYVKSTKLRLATGLRNIPSIQSRGLFGAI 350
                            *************************************:************
 
A/Texas/04/2009              AGFIEGGWTGMVDGWYGYHHQNEQGSGYAADLKSTQNAIDEITNKVNSVI 400
A/Mexico/InDRE4487/2009      AGFIEGGWTGMVDGWYGYHHQNEQGSGYAADLKSTQNAIDEITNKVNSVI 400
A/New_York/18/2009          AGFIEGGWTGMVDGWYGYHHQNEQGSGYAADLKSTQNAIDEITNKVNSVI 400
A/Canada-ON/RV1527/2009      AGFIEGGWTGMVDGWYGYHHQNEQGSGYAADLKSTQNAIDEITNKVNSVI 400
A/California/04/2009        AGFIEGGWTGMVDGWYGYHHQNEQGSGYAADLKSTQNAIDEITNKVNSVI 400
                            **************************************************
 
A/Texas/04/2009              EKMNTQFTAVGKEFNHLEKRIENLNKKVDDGFLDIWTYNAELLVLLENER 450
A/Mexico/InDRE4487/2009      EKMNTQFTAVGKEFNHLEKRIENLNKKVDDGFLDIWTYNAELLVLLENER 450
A/New_York/18/2009          EKMNTQFTAVGKEFNHLEKRIENLNKKVDDGFLDIWTYNAELLVLLENER 450
A/Canada-ON/RV1527/2009      EKMNTQFTAVGKEFNHLEKRIENLNKKVDDGFLDIWTYNAELLVLLENER 450
A/California/04/2009        EKMNTQFTAVGKEFNHLEKRIENLNKKVDDGFLDIWTYNAELLVLLENER 450
                            **************************************************
 
A/Texas/04/2009              TLDYHDSNVKNLYEKVRSQLKNNAKEIGNGCFEFYHKCDNTCMESVKNGT 500
A/Mexico/InDRE4487/2009      TLDYHDSNVKNLYEKVRSQLKNNAKEIGNGCFEFYHKCDNTCMESVKNGT 500
A/New_York/18/2009          TLDYHDSNVKNLYEKVRSQLKNNAKEIGNGCFEFYHKCDNTCMESVKNGT 500
A/Canada-ON/RV1527/2009      TLDYHDSNVKNLYEKVRSQLKNNAKEIGNGCFEFYHKCDNTCMESVKNGT 500
A/California/04/2009        TLDYHDSNVKNLYEKVRSQLKNNAKEIGNGCFEFYHKCDNTCMESVKNGT 500
                            **************************************************
 
A/Texas/04/2009              YDYPKYSEEAKLNREEIDGVKLESTRIYQILAIYSTVASSLVLVVSLGAI 550
A/Mexico/InDRE4487/2009      YDYPKYSEEAKLNREEIDGVKLESTRIYQILAIYSTVASSLVLVVSLGAI 550
A/New_York/18/2009          YDYPKYSEEAKLNREEIDGVKLESTRIYQILAIYSTVASSLVLVVSLGAI 550
A/Canada-ON/RV1527/2009      YDYPKYSEEAKLNREEIDGVKLESTRIYQILAIYSTVASSLVLVVSLGAI 550
A/California/04/2009        YDYPKYSEEAKLNREEIDGVKLESTRIYQILAIYSTVASSLVLVVSLGAI 550
                            **************************************************
 
A/Texas/04/2009              SFWMCSNGSLQCRICI 566
A/Mexico/InDRE4487/2009      SFWMCSNGSLQCRICI 566
A/New_York/18/2009          SFWMCSNGSLQCRICI 566
A/Canada-ON/RV1527/2009      SFWMCSNGSLQCRICI 566
A/California/04/2009        SFWMCSNGSLQCRICI 566
                            ****************
</PRE><SPAN class=3Dpsmall>
 
--------------------
===multiple sequence alignment of NP===
'''NP'''
<PRE>CLUSTAL 2.0.10 =
multiple sequence alignment of NP
 
A/California/04/2009        ------MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMC 44
A/Texas/04/2009              ------MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMC 44
A/Mexico/InDRE4487/2009      MSDIEAMASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMC 50
A/New_York/18/2009          ------MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMC 44
A/Canada-ON/RV1527/2009      MSDIEAMASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMC 50
                                  ********************************************
 
A/California/04/2009        TELKLSDYDGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGG 94
A/Texas/04/2009              TELKLSDYDGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGG 94
A/Mexico/InDRE4487/2009      TELKLSDYDGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGG 100
A/New_York/18/2009          TELKLSDYDGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGG 94
A/Canada-ON/RV1527/2009      TELKLSDYDGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGG 100
                            **************************************************
 
A/California/04/2009        PIYRRVDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLN 144
A/Texas/04/2009              PIYRRVDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLN 144
A/Mexico/InDRE4487/2009      PIYRRVDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLN 150
A/New_York/18/2009          PIYRRIDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLN 144
A/Canada-ON/RV1527/2009      PIYRRIDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLN 150
                            *****:********************************************
 
A/California/04/2009        DATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIAMELI 194
A/Texas/04/2009              DATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIAMELI 194
A/Mexico/InDRE4487/2009      DATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIAMELI 200
A/New_York/18/2009          DATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIAMELI 194
A/Canada-ON/RV1527/2009      DATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIAMELI 200
                            **************************************************
 
A/California/04/2009        RMIKRGINDRNFWRGENGRRTRVAYERMCNILKGKFQTAAQRAMMDQVRE 244
A/Texas/04/2009              RMIKRGINDRNFWRGENGRRTRVAYERMCNILKGKFQTAAQRAMMDQVRE 244
A/Mexico/InDRE4487/2009      RMIKRGINDRNFWRGENGRRTRVAYERMCNILKGKFQTAAQRAMMDQVRE 250
A/New_York/18/2009          RMIKRGINDRNFWRGENGRRTRVAYERMCNILKGKFQTAAQRAMMDQVRE 244
A/Canada-ON/RV1527/2009      RMIKRGINDRNFWRGENGRRTRVAYERMCNILKGKFQTAAQRAMMDQVRE 250
                            **************************************************
 
A/California/04/2009        SRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFERE 294
A/Texas/04/2009              SRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFERE 294
A/Mexico/InDRE4487/2009      SRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFERE 300
A/New_York/18/2009          SRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFERE 294
A/Canada-ON/RV1527/2009      SRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFERE 300
                            **************************************************
 
A/California/04/2009        GYSLVGIDPFKLLQNSQVVSLMRPNENPAHKSQLVWMACHSAAFEDLRVS 344
A/Texas/04/2009              GYSLVGIDPFKLLQNSQVVSLMRPNENPAHKSQLVWMACHSAAFEDLRVS 344
A/Mexico/InDRE4487/2009      GYSLVGIDPFKLLQNSQVVSLMRPNENPAHKSQLVWMACHSAAFEDLRVS 350
A/New_York/18/2009          GYSLVGIDPFKLLQNSQVVSLMRPNENPAHKSQLVWMACHSAAFEDLRVS 344
A/Canada-ON/RV1527/2009      GYSLVGIDPFKLLQNSQVVSLMRPNENPAHKSQLVWMACHSAAFEDLRVS 350
                            **************************************************
 
A/California/04/2009        SFIRGKKVIPRGKLSTRGVQIASNENVETMDSNTLELRSRYWAIRTRSGG 394
A/Texas/04/2009              SFIRGKKVIPRGKLSTRGVQIASNENVETMDSNTLELRSRYWAIRTRSGG 394
A/Mexico/InDRE4487/2009      SFIRGKKVIPRGKLSTRGVQIASNENVETMDSNTLELRSRYWAIRTRSGG 400
A/New_York/18/2009          SFIRGKKVIPRGKLSTRGVQIASNENVETMDSNTLELRSRYWAIRTRSGG 394
A/Canada-ON/RV1527/2009      SFIRGKKVIPRGKLSTRGVQIASNENVETMDSNTLELRSRYWAIRTRSGG 400
                            **************************************************
 
A/California/04/2009        NTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFSGNNEGRTSDMRTEV 444
A/Texas/04/2009              NTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFSGNNEGRTSDMRTEV 444
A/Mexico/InDRE4487/2009      NTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFSGNNEGRTSDMRTEV 450
A/New_York/18/2009          NTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFSGNNEGRTSDMRTEV 444
A/Canada-ON/RV1527/2009      NTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFSGNNEGRTSDMRTEV 450
                            **************************************************
 
A/California/04/2009        IRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAE 494
A/Texas/04/2009              IRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAE 494
A/Mexico/InDRE4487/2009      IRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAE 500
A/New_York/18/2009          IRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAE 494
A/Canada-ON/RV1527/2009      IRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAE 500
                            **************************************************
 
A/California/04/2009        EYDS 498
A/Texas/04/2009              EYDS 498
A/Mexico/InDRE4487/2009      EYDS 504
A/New_York/18/2009          EYDS 498
A/Canada-ON/RV1527/2009      EYDS 504
                            ****
</PRE><SPAN class=3Dpsmall>
 
 
--------------------
===multiple sequence alignment of NA===
'''NA'''
<PRE>CLUSTAL 2.0.10 =
multiple sequence alignment of NA
 
A/California/04/2009        MNPNQKIITIGSVCMTIGMANLILQIGNIISIWISHSIQLGNQNQIETCN 50
A/Texas/04/2009              MNPNQKIITIGSVCMTIGMANLILQIGNIISIWISHSIQLGNQNQIETCN 50
A/Mexico/InDRE4487/2009      MNPNQKIITIGSVCMTIGMANLILQIGNIISIWISHSIQLGNQNQIETCN 50
A/New_York/18/2009          MNPNQKIITIGSVCMTIGMANLILQIGNIISIWISHSIQLGNQNQIETCN 50
A/Canada-ON/RV1527/2009      MNPNQKIITIGSVCMTIGMANLILQIGNIISIWISHSIQLGNQNQIETCN 50
                            **************************************************
 
A/California/04/2009        QSVITYENNTWVNQTYVNISNTNFAAGQSVVSVKLAGNSSLCPVSGWAIY 100
A/Texas/04/2009              QSVITYENNTWVNQTYVNISNTNFAAGQSVVSVKLAGNSSLCPVSGWAIY 100
A/Mexico/InDRE4487/2009      QSVITYENNTWVNQTYVNISNTNFAAGQSVVSVKLAGNSSLCPVSGWAIY 100
A/New_York/18/2009          QSVITYENNTWVNQTYVNISNTNFAAGQSVVSVKLAGNSSLCPVSGWAIY 100
A/Canada-ON/RV1527/2009      QSVITYENNTWVNQTYVNISNTNFAAGQSVVSVKLAGNSSLCPVSGWAIY 100
                            **************************************************
 
A/California/04/2009        SKDNSVRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIK 150
A/Texas/04/2009              SKDNSVRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIK 150
A/Mexico/InDRE4487/2009      SKDNSVRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIK 150
A/New_York/18/2009          SKDNSIRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIK 150
A/Canada-ON/RV1527/2009      SKDNSIRIGSKGDVFVIREPFISCSPLECRTFFLTQGALLNDKHSNGTIK 150
                            *****:********************************************
 
A/California/04/2009        DRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDN 200
A/Texas/04/2009              DRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDN 200
A/Mexico/InDRE4487/2009      DRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDN 200
A/New_York/18/2009          DRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDN 200
A/Canada-ON/RV1527/2009      DRSPYRTLMSCPIGEVPSPYNSRFESVAWSASACHDGINWLTIGISGPDN 200
                            **************************************************
 
A/California/04/2009        GAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQ 250
A/Texas/04/2009              GAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQ 250
A/Mexico/InDRE4487/2009      GAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQ 250
A/New_York/18/2009          GAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSDGQ 250
A/Canada-ON/RV1527/2009      GAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSDGQ 250
                            ***********************************************:**
 
A/California/04/2009        ASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSN 300
A/Texas/04/2009              ASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSN 300
A/Mexico/InDRE4487/2009      ASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSN 300
A/New_York/18/2009          ASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSN 300
A/Canada-ON/RV1527/2009      ASYKIFRIEKGKIVKSVEMNAPNYHYEECSCYPDSSEITCVCRDNWHGSN 300
                            **************************************************
 
A/California/04/2009        RPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFS 350
A/Texas/04/2009              RPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFS 350
A/Mexico/InDRE4487/2009      RPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFS 350
A/New_York/18/2009          RPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFS 350
A/Canada-ON/RV1527/2009      RPWVSFNQNLEYQIGYICSGIFGDNPRPNDKTGSCGPVSSNGANGVKGFS 350
                            **************************************************
 
A/California/04/2009        FKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWS 400
A/Texas/04/2009              FKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWS 400
A/Mexico/InDRE4487/2009      FKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWS 400
A/New_York/18/2009          FKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWS 400
A/Canada-ON/RV1527/2009      FKYGNGVWIGRTKSISSRNGFEMIWDPNGWTGTDNNFSIKQDIVGINEWS 400
                            **************************************************
 
A/California/04/2009        GYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNS 450
A/Texas/04/2009              GYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNS 450
A/Mexico/InDRE4487/2009      GYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNS 450
A/New_York/18/2009          GYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNS 450
A/Canada-ON/RV1527/2009      GYSGSFVQHPELTGLDCIRPCFWVELIRGRPKENTIWTSGSSISFCGVNS 450
                            **************************************************
 
A/California/04/2009        DTVGWSWPDGAELPFTIDK 469
A/Texas/04/2009              DTVGWSWPDGAELPFTIDK 469
A/Mexico/InDRE4487/2009      DTVGWSWPDGAELPFTIDK 469
A/New_York/18/2009          DTVGWSWPDGAELPFTIDK 469
A/Canada-ON/RV1527/2009      DTVGWSWPDGAELPFTIDK 469
                            *******************
</PRE><SPAN class=3Dpsmall>
 
--------------------
===multiple sequence alignment of MP===
'''MP'''
<PRE>CLUSTAL 2.0.10 =
multiple sequence alignment of MP
 
A/California/04/2009        ----TEVETYVLSIIPSGPLKAEIAQRLESVFAGKNTDLEALMEWLKTRP 46
A/Texas/04/2009              MSLLTEVETYVLSIIPSGPLKAEIAQRLESVFAGKNTDLEALMEWLKTRP 50
A/New_York/18/2009          MSLLTEVETYVLSIIPSGPLKAEIAQRLESVFAGKNTDLEALMEWLKTRP 50
A/Mexico/InDRE4487/2009      MSLLTEVETYVLSIIPSGPLKAEIAQRLESVFAGKNTDLEALMEWLKTRP 50
A/Canada-ON/RV1527/2009      MSLLTEVETYVLSIIPSGPLKAEIAQRLESVFAGKNTDLEALMEWLKTRP 50
                                **********************************************
 
A/California/04/2009        ILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLY 96
A/Texas/04/2009              ILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLY 100
A/New_York/18/2009          ILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLY 100
A/Mexico/InDRE4487/2009      ILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLY 100
A/Canada-ON/RV1527/2009      ILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLY 100
                            **************************************************
 
A/California/04/2009        KKLKREITFHGAKEVSLSYSTGALASCMGLIYNRMGTVTTEAAFGLVCAT 146
A/Texas/04/2009              KKLKREITFHGAKEVSLSYSTGALASCMGLIYNRMGTVTTEAAFGLVCAT 150
A/New_York/18/2009          KKLKREITFHGAKEVSLSYSTGALASCMGLIYNRMGTVTTEAAFGLVCAT 150
A/Mexico/InDRE4487/2009      KKLKREITFHGAKEVSLSYSTGALASCMGLIYNRMGTVTTEAAFGLVCAT 150
A/Canada-ON/RV1527/2009      KKLKREITFHGAKEVSLSYSTGALASCMGLIYNRMGTVTTEAAFGLVCAT 150
                            **************************************************
 
A/California/04/2009        CEQIADSQHRSHRQMATTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAA 196
A/Texas/04/2009              CEQIADSQHRSHRQMATTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAA 200
A/New_York/18/2009          CEQIADSQHRSHRQMATTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAA 200
A/Mexico/InDRE4487/2009      CEQIADSQHRSHRQMATTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAA 200
A/Canada-ON/RV1527/2009      CEQIADSQHRSHRQMATTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAA 200
                            **************************************************
 
A/California/04/2009        EAMEVANQTRQMVHAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQR 246
A/Texas/04/2009              EAMEVANQTRQMVHAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQR 250
A/New_York/18/2009          EAMEVANQTRQMVHAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQR 250
A/Mexico/InDRE4487/2009      EAMEVANQTRQMVHAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQR 250
A/Canada-ON/RV1527/2009      EAMEVANQTRQMVHAMRTIGTHPSSSTGLKDDLLENLQAYQKRMGVQMQR 250
                            **************************:***********************
 
A/California/04/2009        FK 248
A/Texas/04/2009              FK 252
A/New_York/18/2009          FK 252
A/Mexico/InDRE4487/2009      FK 252
A/Canada-ON/RV1527/2009      FK 252
                            **
</PRE><SPAN class=3Dpsmall>
 
--------------------
===multiple sequence alignment of NS===
'''NS'''
<PRE>CLUSTAL 2.0.10 =
multiple sequence alignment of NS
 
A/California/04/2009        MDSNTMSSFQVDCFLWHIRKRFADNGLGDAPFLDRLRRDQKSLKGRGNTL 50
A/Texas/04/2009              MDSNTMSSFQVDCFLWHIRKRFADNGLGDAPFLDRLRRDQKSLKGRGNTL 50
A/Mexico/InDRE4487/2009      MDSNTMSSFQVDCFLWHIRKRFADNGLGDAPFLDRLRRDQKSLKGRGNTL 50
A/New_York/18/2009          MDSNTMSSFQVDCFLWHIRKRFADNGLGDAPFLDRLRRDQKSLKGRGNTL 50
A/Canada-ON/RV1527/2009      MDSNTMSSFQVDCFLWHIRKRFADNGLGDAPFLDRLRRDQKSLKGRGNTL 50
                            **************************************************
 
A/California/04/2009        GLDIETATLVGKQIVEWILKEESSETLRMTIASVPTSRYLSDMTLEEMSR 100
A/Texas/04/2009              GLDIETATLVGKQIVEWILKEESSETLRMTIASVPTSRYLSDMTLEEMSR 100
A/Mexico/InDRE4487/2009      GLDIETATLVGKQIVEWILKEESSETLRMTIASVPTSRYLSDMTLEEMSR 100
A/New_York/18/2009          GLDIETATLVGKQIVEWILKEESSETLRMTIASVPTSRYLSDMTLEEMSR 100
A/Canada-ON/RV1527/2009      GLDIETATLVGKQIVEWILKEESSETLRMTIASVPTSRYLSDMTLEEMSR 100
                            **************************************************
 
A/California/04/2009        DWFMLMPRQKIIGPLCVRLDQAIMEKNIVLKANFSVIFNRLETLILLRAF 150
A/Texas/04/2009              DWFMLMPRQKIIGPLCVRLDQAIMEKNIVLKANFSVIFNRLETLILLRAF 150
A/Mexico/InDRE4487/2009      DWFMLMPRQKIIGPLCVRLDQAIMEKNIVLKANFSVIFNRLETLILLRAF 150
A/New_York/18/2009          DWFMLMPRQKIIGPLCVRLDQAVMEKNIVLKANFSVIFNRLETLILLRAF 150
A/Canada-ON/RV1527/2009      DWFMLMPRQKIIGPLCVRLDQAVMEKNIVLKANFSVIFNRLETLILLRAF 150
                            **********************:***************************
 
A/California/04/2009        TEEGAIVGEISPLPSLPGHTYEDVKNAVGVLIGGLEWNGNTVRVSENIQR 200
A/Texas/04/2009              TEEGAIVGEISPLPSLPGHTYEDVKNAVGVLIGGLEWNGNTVRVSENIQR 200
A/Mexico/InDRE4487/2009      TEEGAIVGEISPLPSLPGHTYEDVKNAVGVLIGGLEWNGNTVRVSENIQR 200
A/New_York/18/2009          TEEGAIVGEISPLPSLPGHTYEDVKNAVGVLIGGLEWNGNTVRVSENIQR 200
A/Canada-ON/RV1527/2009      TEEGAIVGEISPLPSLPGHTYEDVKNAVGVLIGGLEWNGNTVRVSENIQR 200
                            **************************************************
 
A/California/04/2009        FAWRNCDENGRPSLPPEQK 219
A/Texas/04/2009              FAWRNCDENGRPSLPPEQK 219
A/Mexico/InDRE4487/2009      FAWRNCDENGRPSLPPEQK 219
A/New_York/18/2009          FAWRNCDENGRPSLPPEQK 219
A/Canada-ON/RV1527/2009      FAWRNCDENGRPSLPPEQK 219
                            *******************
</PRE><SPAN class=3Dpsmall>
Retrieved from "https://proteopedia.org/User:Michael_Strong/H1N1"