3dk5: Difference between revisions

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{{Seed}}
[[Image:3dk5.jpg|left|200px]]


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==Crystal Structure of Apo-GlmU from Mycobacterium tuberculosis==
The line below this paragraph, containing "STRUCTURE_3dk5", creates the "Structure Box" on the page.
<StructureSection load='3dk5' size='340' side='right'caption='[[3dk5]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3dk5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DK5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3dk5|  PDB=3dk5  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dk5 OCA], [https://pdbe.org/3dk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dk5 RCSB], [https://www.ebi.ac.uk/pdbsum/3dk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dk5 ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Apo-GlmU from Mycobacterium tuberculosis===
== Function ==
 
[https://www.uniprot.org/uniprot/GLMU_MYCTU GLMU_MYCTU] Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.<ref>PMID:19237750</ref> <ref>PMID:19121323</ref>
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_19121323}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/3dk5_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_19121323}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3DK5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DK5 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dk5 ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:19121323</ref><references group="xtra"/>
<references/>
[[Category: Mycobacterium tuberculosis]]
__TOC__
[[Category: Prakash, B.]]
</StructureSection>
[[Category: Verma, S K.]]
[[Category: Large Structures]]
[[Category: Acetyltransferase]]
[[Category: Mycobacterium tuberculosis H37Ra]]
[[Category: Bifunctional]]
[[Category: Prakash B]]
[[Category: Cell shape]]
[[Category: Verma SK]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Cytoplasm]]
[[Category: Left-handed-beta-helix]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Multifunctional enzyme]]
[[Category: Nucleotidyltransferase]]
[[Category: Peptidoglycan synthesis]]
[[Category: Pyrophosphorylase]]
[[Category: Rossmann-like fold]]
[[Category: Transferase]]
[[Category: Trimer]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 17:06:03 2009''

Latest revision as of 08:24, 20 March 2024

Crystal Structure of Apo-GlmU from Mycobacterium tuberculosis

3dk5, resolution 2.23Å

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