3fw7: Difference between revisions
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< | ==Structure of berberine bridge enzyme, H104A variant== | ||
<StructureSection load='3fw7' size='340' side='right'caption='[[3fw7]], [[Resolution|resolution]] 1.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3fw7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FW7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.825Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fw7 OCA], [https://pdbe.org/3fw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fw7 RCSB], [https://www.ebi.ac.uk/pdbsum/3fw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fw7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fw7_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fw7 ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Reticuline oxidase|Reticuline oxidase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Eschscholzia californica]] | [[Category: Eschscholzia californica]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Gruber | [[Category: Gruber K]] | ||
[[Category: Macheroux | [[Category: Macheroux P]] | ||
[[Category: Winkler | [[Category: Winkler A]] | ||
Latest revision as of 01:49, 21 November 2024
Structure of berberine bridge enzyme, H104A variant
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