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The shown representation is a DNA:RAN hybrid duplex. This is the  
The shown representation is a DNA:RAN hybrid duplex. This is the  
<scene name='Sandbox1234/Dna/1'>DNA</scene> in orange and this is the <scene name='Sandbox1234/Rna/1'>RNA</scene> in green. We can choose to see the base pairs, which show very neatly. First, the G-C pairs: <scene name='Sandbox1234/Dg-c/1'>dG-C</scene> are in blue and dC-G are in yellow. Similarly, we can see the dA-U in red and the dT-A in purple (note that the RNA has U nucleotides instead of T). Furthermore, we can also see the purine and pyrimidine for a more general view of the bases. Because this is the B form of DNA:RNA interaction, all hydrogen bonds between the bases are through the Watson Crick faces. If we choose to see the ions, as we'd expect, the whole complex shines.
<scene name='Sandbox1234/Dna/1'>DNA</scene> in orange and this is the <scene name='Sandbox1234/Rna/1'>RNA</scene> in green. Notice that all hydrogen bonds between the bases are linear. We can choose to see the base pairs, which show very neatly. First, the G-C pairs: <scene name='Sandbox1234/Dg-c/1'>dG-C</scene> are in blue and dC-G are in yellow. Similarly, we can see the dA-U in red and the dT-A in purple (note that the RNA has U nucleotides instead of T). Furthermore, we can also see the purine and pyrimidine for a more general view of the bases. Because this is the B form of DNA:RNA interaction, all hydrogen bonds between the bases are through the Watson Crick faces. If we choose to see the ions, as we'd expect, the whole complex shines.




===Reference===
===Reference===
http://www.rcsb.org/pdb/explore.do?structureId=124d
http://www.rcsb.org/pdb/explore.do?structureId=124d

Latest revision as of 13:57, 23 May 2009

This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!

DNA:RNA interactions

Drag the structure with the mouse to rotate
124d, 1 NMR models (default scene)
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



The shown representation is a DNA:RAN hybrid duplex. This is the DNA in orange and this is the RNA in green. Notice that all hydrogen bonds between the bases are linear. We can choose to see the base pairs, which show very neatly. First, the G-C pairs: dG-C are in blue and dC-G are in yellow. Similarly, we can see the dA-U in red and the dT-A in purple (note that the RNA has U nucleotides instead of T). Furthermore, we can also see the purine and pyrimidine for a more general view of the bases. Because this is the B form of DNA:RNA interaction, all hydrogen bonds between the bases are through the Watson Crick faces. If we choose to see the ions, as we'd expect, the whole complex shines.


Reference

https://www.rcsb.org/pdb/explore.do?structureId=124d