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New page: left|200px<br /><applet load="1rna" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rna, resolution 2.250Å" /> '''CRYSTALLOGRAPHIC ST...
 
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[[Image:1rna.gif|left|200px]]<br /><applet load="1rna" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1rna, resolution 2.250&Aring;" />
'''CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2'''<br />


==Overview==
==CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2==
The crystallographic structure of the synthetic oligoribonucleotide, U(UA)6A, has been solved at 2.25 A resolution. The crystallographic, refinement permitted the identification of 91 solvent molecules, with a, final agreement factor of 13%. The molecule is a dimer of 14 base-pairs, and shows the typical features of an A-type helix. However, the presence, of two kinks causes a divergence from a straight helix. The observed, deformation, which is stabilized by a few hydrogen bonds in the crystal, packing, could be due to the relatively high (35 degrees C) temperature of, crystallization. The complete analysis of the structure is presented. It, includes the stacking geometries, the backbone conformation and the, solvation.
<StructureSection load='1rna' size='340' side='right'caption='[[1rna]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1rna]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RNA FirstGlance]. <br>
1RNA is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RNA OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rna OCA], [https://pdbe.org/1rna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rna RCSB], [https://www.ebi.ac.uk/pdbsum/1rna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rna ProSAT]</span></td></tr>
==Reference==
</table>
Crystallographic structure of an RNA helix: [U(UA)6A]2., Dock-Bregeon AC, Chevrier B, Podjarny A, Johnson J, de Bear JS, Gough GR, Gilham PT, Moras D, J Mol Biol. 1989 Oct 5;209(3):459-74. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2479753 2479753]
__TOC__
[[Category: Protein complex]]
</StructureSection>
[[Category: Bear, J.S.De.]]
[[Category: Large Structures]]
[[Category: Chevrier, B.]]
[[Category: Chevrier B]]
[[Category: Dock-Bregeon, A.C.]]
[[Category: De Bear JS]]
[[Category: Gilham, P.T.]]
[[Category: Dock-Bregeon AC]]
[[Category: Gough, G.R.]]
[[Category: Gilham PT]]
[[Category: Johnson, J.]]
[[Category: Gough GR]]
[[Category: Moras, D.]]
[[Category: Johnson J]]
[[Category: Podjarny, A.]]
[[Category: Moras D]]
[[Category: a-rna]]
[[Category: Podjarny A]]
[[Category: double helix]]
 
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