2kj6: Difference between revisions
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==NMR Solution Structure of a Tubulin folding cofactor B obtained from Arabidopsis thaliana: Northeast Structural Genomics Consortium target AR3436A== | |||
<StructureSection load='2kj6' size='340' side='right'caption='[[2kj6]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2kj6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJ6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj6 OCA], [https://pdbe.org/2kj6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kj6 RCSB], [https://www.ebi.ac.uk/pdbsum/2kj6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kj6 ProSAT], [https://www.topsan.org/Proteins/NESGC/2kj6 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TBCB_ARATH TBCB_ARATH] Involved in control of cell division. Regulates probably the availability of alpha-tubulin for dimerization of alpha-/beta-tubulin, which is required for proper microtubule biogenesis. Decreased expression of TFCB results in enlarged mesophyll cells and leaf epidermal cells with bulged nuclei, increased ploidy and increased numbers of spindles and phragmoplasts.<ref>PMID:20036919</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kj6_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kj6 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Large Structures]] | |||
[[Category: Acton T]] | |||
[[Category: Ciccosanti C]] | |||
[[Category: Everett J]] | |||
[[Category: Foote E]] | |||
[[Category: Huang YJ]] | |||
[[Category: Jiang M]] | |||
[[Category: Mani R]] | |||
[[Category: Montelione GT]] | |||
[[Category: Nair R]] | |||
[[Category: Rost B]] | |||
[[Category: Shastry R]] | |||
[[Category: Swapna GVT]] | |||
[[Category: Xiao R]] | |||
Latest revision as of 09:48, 9 May 2024
NMR Solution Structure of a Tubulin folding cofactor B obtained from Arabidopsis thaliana: Northeast Structural Genomics Consortium target AR3436A
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