3dht: Difference between revisions

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{{Seed}}
[[Image:3dht.jpg|left|200px]]


<!--
==The Crystal Structure Determination of Rat (rattus norvegicus) Hemoglobin==
The line below this paragraph, containing "STRUCTURE_3dht", creates the "Structure Box" on the page.
<StructureSection load='3dht' size='340' side='right'caption='[[3dht]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3dht]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DHT FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.98&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
{{STRUCTURE_3dht|  PDB=3dht  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dht OCA], [https://pdbe.org/3dht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dht RCSB], [https://www.ebi.ac.uk/pdbsum/3dht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dht ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HBA_RAT HBA_RAT] Involved in oxygen transport from the lung to the various peripheral tissues.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dh/3dht_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dht ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Crystal structure of hemoglobin isolated from the Brazilian maned wolf (Chrysocyon brachyurus) was determined using standard molecular replacement technique and refined using maximum-likelihood and simulated annealing protocols to 1.87A resolution. Structural and functional comparisons between hemoglobins from the Chrysocyon brachyurus and Homo sapiens are discussed, in order to provide further insights in the comparative biochemistry of vertebrate hemoglobins.


===The Crystal Structure Determination of Rat (rattus norvegicus) Hemoglobin===
Crystal structure of hemoglobin from the maned wolf (Chrysocyon brachyurus) using synchrotron radiation.,Fadel V, Canduri F, Olivieri JR, Smarra AL, Colombo MF, Bonilla-Rodriguez GO, de Azevedo WF Jr Protein Pept Lett. 2003 Dec;10(6):551-9. PMID:014683506<ref>PMID:014683506</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 3dht" style="background-color:#fffaf0;"></div>


==About this Structure==
==See Also==
3DHT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHT OCA].
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:14683506</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Balasubramanian, M.]]
[[Category: Balasubramanian M]]
[[Category: Moorthy, Pon Sathya.]]
[[Category: Neelagandan K]]
[[Category: Neelagandan, K.]]
[[Category: Ponnuswamy MN]]
[[Category: Ponnuswamy, M N.]]
[[Category: Sathya Moorthy P]]
[[Category: Sundaresan, S.]]
[[Category: Sundaresan S]]
[[Category: Crystal structure]]
[[Category: Heme]]
[[Category: Hemoglobin]]
[[Category: Iron]]
[[Category: Metal-binding]]
[[Category: Oxygen storage]]
[[Category: Oxygen transport]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Transport]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  1 09:35:24 2009''
Retrieved from "https://proteopedia.org/3dht"