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New page: left|200px<br /><applet load="1nni" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nni, resolution 2.50Å" /> '''Azobenzene Reductase...
 
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[[Image:1nni.gif|left|200px]]<br /><applet load="1nni" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1nni, resolution 2.50&Aring;" />
'''Azobenzene Reductase from Bacillus subtilis'''<br />


==About this Structure==
==Azobenzene Reductase from Bacillus subtilis==
1NNI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] with FMN as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Azobenzene_reductase Azobenzene reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.6 1.7.1.6] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NNI OCA].  
<StructureSection load='1nni' size='340' side='right'caption='[[1nni]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
[[Category: Azobenzene reductase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1nni]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NNI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nni OCA], [https://pdbe.org/1nni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nni RCSB], [https://www.ebi.ac.uk/pdbsum/1nni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nni ProSAT], [https://www.topsan.org/Proteins/MCSG/1nni TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AZR_BACSU AZR_BACSU] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an electron donor for its activity.<ref>PMID:16752898</ref> <ref>PMID:16861800</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nn/1nni_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nni ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Collart, F.]]
[[Category: Collart F]]
[[Category: Cuff, M.E.]]
[[Category: Cuff ME]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak A]]
[[Category: Kim, Y.]]
[[Category: Kim Y]]
[[Category: MCSG, Midwest.Center.for.Structural.Genomics.]]
[[Category: Maj L]]
[[Category: Maj, L.]]
[[Category: FMN]]
[[Category: azobenzene reductase]]
[[Category: azoreductase]]
[[Category: flavoproteins]]
[[Category: mcsg]]
[[Category: midwest center for structural genomics]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 23:26:28 2007''

Latest revision as of 08:51, 10 April 2024

Azobenzene Reductase from Bacillus subtilis

1nni, resolution 2.50Å

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