3h6r: Difference between revisions

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'''Unreleased structure'''


The entry 3h6r is ON HOLD
==Clitocypin, a beta-trefoil cysteine protease inhibitor==
 
<StructureSection load='3h6r' size='340' side='right'caption='[[3h6r]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
Authors: Renko, M., Sabotic, J., Brzin, J., Turk, D.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3h6r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clitocybe_nebularis Clitocybe nebularis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H6R FirstGlance]. <br>
Description: Clitocypin, a Kunitz type cysteine protease inhibitor
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.948&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h6r OCA], [https://pdbe.org/3h6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h6r RCSB], [https://www.ebi.ac.uk/pdbsum/3h6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h6r ProSAT]</span></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  8 09:14:09 2009''
</table>
== Function ==
[https://www.uniprot.org/uniprot/CLIT2_CLINE CLIT2_CLINE] Binds and inhibits cysteine proteinases. Inhibits most strongly papain and cathepsin L, more weakly bromelain and cathepsin B while it is completely ineffective against cathepsin H.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/3h6r_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h6r ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Clitocybe nebularis]]
[[Category: Large Structures]]
[[Category: Brzin J]]
[[Category: Renko M]]
[[Category: Sabotic J]]
[[Category: Turk D]]
Retrieved from "https://proteopedia.org/3h6r"