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New page: left|200px<br /><applet load="1jly" size="450" color="white" frame="true" align="right" spinBox="true" caption="1jly, resolution 2.2Å" /> '''CRYSTAL STRUCTURE OF ...
 
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[[Image:1jly.gif|left|200px]]<br /><applet load="1jly" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1jly, resolution 2.2&Aring;" />
'''CRYSTAL STRUCTURE OF AMARANTHUS CAUDATUS AGGLUTININ'''<br />


==Overview==
==CRYSTAL STRUCTURE OF AMARANTHUS CAUDATUS AGGLUTININ==
Amaranthus caudatus agglutinin contains a novel arrangement of four, beta-trefoil domains. The sugar-binding site provides specificity for the, carcinoma-associated T-antigen disaccharide even when 'masked' by other, sugars.
<StructureSection load='1jly' size='340' side='right'caption='[[1jly]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1jly]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Amaranthus_caudatus Amaranthus caudatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JLY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jly OCA], [https://pdbe.org/1jly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jly RCSB], [https://www.ebi.ac.uk/pdbsum/1jly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jly ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q71QF2_AMACA Q71QF2_AMACA]
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Amaranthus caudatus agglutinin contains a novel arrangement of four beta-trefoil domains. The sugar-binding site provides specificity for the carcinoma-associated T-antigen disaccharide even when 'masked' by other sugars.


==About this Structure==
Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin.,Transue TR, Smith AK, Mo H, Goldstein IJ, Saper MA Nat Struct Biol. 1997 Oct;4(10):779-83. PMID:9334739<ref>PMID:9334739</ref>
1JLY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Amaranthus_caudatus Amaranthus caudatus] with FOR as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JLY OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin., Transue TR, Smith AK, Mo H, Goldstein IJ, Saper MA, Nat Struct Biol. 1997 Oct;4(10):779-83. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9334739 9334739]
</div>
<div class="pdbe-citations 1jly" style="background-color:#fffaf0;"></div>
 
==See Also==
*[[Agglutinin 3D structures|Agglutinin 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Amaranthus caudatus]]
[[Category: Amaranthus caudatus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Goldstein, I.J.]]
[[Category: Goldstein IJ]]
[[Category: Mo, H.]]
[[Category: Mo H]]
[[Category: Saper, M.A.]]
[[Category: Saper MA]]
[[Category: Smith, A.K.]]
[[Category: Smith AK]]
[[Category: Transue, T.R.]]
[[Category: Transue TR]]
[[Category: FOR]]
[[Category: agglutinin]]
[[Category: bivalent]]
[[Category: lectin]]
[[Category: t-disaccharide homodimer]]
 
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