2wns: Difference between revisions
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New page: '''Unreleased structure''' The entry 2wns is ON HOLD Authors: Moche, M., Roos, A., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Grasl... |
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''' | ==HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE (OPRTASE) DOMAIN OF URIDINE 5'-MONOPHOSPHATE SYNTHASE (UMPS) IN COMPLEX WITH ITS SUBSTRATE OROTIDINE 5'-MONOPHOSPHATE (OMP)== | ||
<StructureSection load='2wns' size='340' side='right' caption='[[2wns]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2wns]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNS FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OMP:OROTIDINE-5-MONOPHOSPHATE'>OMP</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jgy|2jgy]], [[2v30|2v30]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wns OCA], [http://pdbe.org/2wns PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wns RCSB], [http://www.ebi.ac.uk/pdbsum/2wns PDBsum]</span></td></tr> | |||
</table> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wns_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wns ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]] | |||
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
[[Category: Orotate phosphoribosyltransferase]] | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: Berglund, H]] | |||
[[Category: Bountra, C]] | |||
[[Category: Collins, R]] | |||
[[Category: Edwards, A M]] | |||
[[Category: Flodin, S]] | |||
[[Category: Flores, A]] | |||
[[Category: Graslund, S]] | |||
[[Category: Hammarstrom, M]] | |||
[[Category: Johansson, A]] | |||
[[Category: Johansson, I]] | |||
[[Category: Karlberg, T]] | |||
[[Category: Kotyenova, T]] | |||
[[Category: Kotzch, A]] | |||
[[Category: Moche, M]] | |||
[[Category: Nielsen, T K]] | |||
[[Category: Nordlund, P]] | |||
[[Category: Nyman, T]] | |||
[[Category: Persson, C]] | |||
[[Category: Roos, A]] | |||
[[Category: Sagemark, J]] | |||
[[Category: Schueler, H]] | |||
[[Category: Schutz, P]] | |||
[[Category: Siponen, M I]] | |||
[[Category: Svensson, L]] | |||
[[Category: Thorsell, A G]] | |||
[[Category: Tresaugues, L]] | |||
[[Category: Vandenberg, S]] | |||
[[Category: Weigelt, J]] | |||
[[Category: Welin, M]] | |||
[[Category: Wisniewska, M]] | |||
[[Category: Decarboxylase]] | |||
[[Category: Disease mutation]] | |||
[[Category: Glycosyltransferase]] | |||
[[Category: Lyase]] | |||
[[Category: Multifunctional enzyme]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Pyrimidine biosynthesis]] | |||
[[Category: Transferase]] | |||