3ehq: Difference between revisions
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==Crystal Structure of Human Osteoclast Stimulating Factor== | |||
<StructureSection load='3ehq' size='340' side='right'caption='[[3ehq]], [[Resolution|resolution]] 2.57Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3ehq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EHQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ehq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ehq OCA], [https://pdbe.org/3ehq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ehq RCSB], [https://www.ebi.ac.uk/pdbsum/3ehq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ehq ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/OSTF1_HUMAN OSTF1_HUMAN] Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.<ref>PMID:10092216</ref> | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
== | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/3ehq_consurf.spt"</scriptWhenChecked> | ||
< | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ehq ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Gao | [[Category: Large Structures]] | ||
[[Category: Niu | [[Category: Gao Y]] | ||
[[Category: Teng | [[Category: Niu L]] | ||
[[Category: Tong | [[Category: Teng M]] | ||
[[Category: Zhang | [[Category: Tong S]] | ||
[[Category: Zhou | [[Category: Zhang X]] | ||
[[Category: Zhu | [[Category: Zhou H]] | ||
[[Category: Zhu Z]] | |||
Latest revision as of 01:46, 21 November 2024
Crystal Structure of Human Osteoclast Stimulating Factor
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