3i55: Difference between revisions

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'''Unreleased structure'''


The entry 3i55 is ON HOLD  until sometime in the future
==Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit==
 
<StructureSection load='3i55' size='340' side='right'caption='[[3i55]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
Authors: Gurel, G., Blaha, G., Steitz, T.A., Moore, P.B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3i55]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui] and [https://en.wikipedia.org/wiki/Haloarcula_marismortui_ATCC_43049 Haloarcula marismortui ATCC 43049]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I55 FirstGlance]. <br>
Description: Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=2OP:(2S)-2-HYDROXYPROPANOIC+ACID'>2OP</scene>, <scene name='pdbligand=5AA:N6-DIMETHYL-3-AMINO-ADENOSINE-5-MONOPHOSPHATE'>5AA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYL:MYCALAMIDE+A'>MYL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PO2:HYPOPHOSPHITE'>PO2</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep  3 15:20:17 2009''
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i55 OCA], [https://pdbe.org/3i55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i55 RCSB], [https://www.ebi.ac.uk/pdbsum/3i55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i55 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL2_HALMA RL2_HALMA] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).[HAMAP-Rule:MF_01320_A]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i55_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i55 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui ATCC 43049]]
[[Category: Large Structures]]
[[Category: Blaha G]]
[[Category: Gurel G]]
[[Category: Moore PB]]
[[Category: Steitz TA]]