3ir3: Difference between revisions
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New page: '''Unreleased structure''' The entry 3ir3 is ON HOLD Authors: Ugochukwu, E., Cocking, R., Burgess-Brown, N., Pilka, E., Muniz, J., Krojer, T., Chaikuad, A., Gileadi, O., Bountra, C., Ar... |
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==Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)== | |||
<StructureSection load='3ir3' size='340' side='right'caption='[[3ir3]], [[Resolution|resolution]] 1.99Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3ir3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IR3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ir3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ir3 OCA], [https://pdbe.org/3ir3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ir3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ir3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ir3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HTD2_HUMAN HTD2_HUMAN] Mitochondrial 3-hydroxyacyl-thioester dehydratase, which may be involved in fatty acid biosynthesis.<ref>PMID:17898086</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ir/3ir3_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ir3 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bountra C]] | |||
[[Category: Burgess-Brown N]] | |||
[[Category: Chaikuad A]] | |||
[[Category: Cocking R]] | |||
[[Category: Edwards A]] | |||
[[Category: Gileadi O]] | |||
[[Category: Kavanagh KL]] | |||
[[Category: Krojer T]] | |||
[[Category: Muniz J]] | |||
[[Category: Oppermann U]] | |||
[[Category: Pilka E]] | |||
[[Category: Ugochukwu E]] | |||
[[Category: Weigelt J]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 07:56, 6 September 2023
Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)
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