3id1: Difference between revisions

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{{Seed}}
[[Image:3id1.png|left|200px]]


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==Crystal Structure of RseP PDZ1 domain==
The line below this paragraph, containing "STRUCTURE_3id1", creates the "Structure Box" on the page.
<StructureSection load='3id1' size='340' side='right'caption='[[3id1]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3id1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ID1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3id1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id1 OCA], [https://pdbe.org/3id1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3id1 RCSB], [https://www.ebi.ac.uk/pdbsum/3id1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3id1 ProSAT]</span></td></tr>
{{STRUCTURE_3id1|  PDB=3id1  |  SCENE=  }}
</table>
 
== Function ==
===Crystal Structure of RseP PDZ1 domain===
[https://www.uniprot.org/uniprot/RSEP_ECOLI RSEP_ECOLI] A site-2 regulated intramembrane protease (S2P) that cleaves the peptide bond between 'Ala-108' and 'Cys-109' in the transmembrane region of RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. Acts on DegS-cleaved RseA to release the cytoplasmic domain of RseA, residue "Val-148" of RseA may be required for this. This provides the cell with sigma-E (RpoE) activity through the proteolysis of RseA. Can also cleave sequences in transmembrane regions of other proteins (such as LacY) as well as liberated signal peptides of beta-lactamase, OmpF, LivK, SecM, PhoA, LivJ, OmpC, Lpp and TorA, probably within the membrane.<ref>PMID:11750129</ref> <ref>PMID:12183368</ref> <ref>PMID:12183369</ref> <ref>PMID:15496982</ref> <ref>PMID:18268014</ref> <ref>PMID:21810987</ref> <ref>PMID:18945679</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_19706448}}, adds the Publication Abstract to the page
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/id/3id1_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_19706448}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3id1 ConSurf].
3ID1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID1 OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:19706448</ref><references group="xtra"/>
__TOC__
[[Category: Escherichia coli k-12]]
</StructureSection>
[[Category: Feng, L.]]
[[Category: Escherichia coli K-12]]
[[Category: Li, X.]]
[[Category: Large Structures]]
[[Category: Shi, Y.]]
[[Category: Feng L]]
[[Category: Wang, B.]]
[[Category: Li X]]
[[Category: Wang, J.]]
[[Category: Shi Y]]
[[Category: Cell inner membrane]]
[[Category: Wang B]]
[[Category: Cell membrane]]
[[Category: Wang J]]
[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Metalloprotease]]
[[Category: Protease]]
[[Category: Transmembrane]]
[[Category: Zinc]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep  9 08:31:41 2009''
Retrieved from "https://proteopedia.org/3id1"