1x0a: Difference between revisions

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New page: left|200px<br /><applet load="1x0a" size="450" color="white" frame="true" align="right" spinBox="true" caption="1x0a, resolution 2.00Å" /> '''Crystal Structure of...
 
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[[Image:1x0a.gif|left|200px]]<br /><applet load="1x0a" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1x0a, resolution 2.00&Aring;" />
'''Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8'''<br />


==About this Structure==
==Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8==
1X0A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with NA and FMT as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1X0A OCA].
<StructureSection load='1x0a' size='340' side='right'caption='[[1x0a]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: L-lactate dehydrogenase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1x0a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X0A FirstGlance]. <br>
[[Category: Thermus thermophilus]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Kunishima, N.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
[[Category: Mizutani, H.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x0a OCA], [https://pdbe.org/1x0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x0a RCSB], [https://www.ebi.ac.uk/pdbsum/1x0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x0a ProSAT], [https://www.topsan.org/Proteins/RSGI/1x0a TOPSAN]</span></td></tr>
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
</table>
[[Category: FMT]]
== Function ==
[[Category: NA]]
[https://www.uniprot.org/uniprot/Q53W84_THET8 Q53W84_THET8]  
[[Category: malate dehydrogenase]]
== Evolutionary Conservation ==
[[Category: riken structural genomics/proteomics initiative]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: rsgi]]
Check<jmol>
[[Category: structural genomics]]
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x0/1x0a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x0a ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 01:10:16 2007''
==See Also==
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Kunishima N]]
[[Category: Mizutani H]]