3ghv: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3ghv]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GHV OCA]. | |||
==See Also== | |||
*[[Dihydrofolate reductase]] | |||
==Reference== | ==Reference== | ||
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[[Category: One-carbon metabolism]] | [[Category: One-carbon metabolism]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 22:45, 26 December 2010
Human dihydrofolate reductase Q35K/N64F double mutant inhibitor complex
Template:ABSTRACT PUBMED 19719239
About this Structure
3ghv is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Gangjee A, Li W, Kisliuk RL, Cody V, Pace J, Piraino J, Makin J. Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents. J Med Chem. 2009 Aug 13;52(15):4892-902. PMID:19719239 doi:10.1021/jm900490a
