1t6s: Difference between revisions

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[[Image:1t6s.jpg|left|200px]]<br /><applet load="1t6s" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1t6s.jpg|left|200px]]<br /><applet load="1t6s" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1t6s, resolution 1.95Å" />

'''Crystal structure of a conserved hypothetical protein from Chlorobium tepidum'''<br />

==Overview==

Structural maintenance of chromosome (SMC) proteins are essential in, chromosome condensation and interact with non-SMC proteins in eukaryotes, and with segregation and condensation proteins (ScpA and ScpB) in, prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405, encodes ScpB (ScpB_ChTe). The high resolution crystal structure of, ScpB_ChTe shows that the monomeric structure consists of two similarly, shaped globular domains composed of three helices sided by beta-strands [a, winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain, of Scc1, a functionally related eukaryotic ScpA homolog, as well as in, many DNA binding proteins.

Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.

==About this Structure==

1T6S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls] with NO3 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA].

1T6S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls] with <scene name='pdbligand=NO3:'>NO3</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA].

==Reference==

Line 13:

[[Category: Chlorobium tepidum tls]]

[[Category: Single protein]]

[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]

[[Category: BSGC, Berkeley Structural Genomics Center.]]

[[Category: Kim, J.S.]]

[[Category: Kim, J S.]]

[[Category: Kim, R.]]

[[Category: Kim, S.H.]]

[[Category: Kim, S H.]]

[[Category: Shin, D.H.]]

[[Category: Shin, D H.]]

[[Category: NO3]]

[[Category: a winged helix-turn-helix]]

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[[Category: structural genomics]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Sun Nov 25 01~~:46:~~01 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:10:28 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1t6s.jpg|left|200px]]<br /><applet load="1t6s" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1t6s.jpg|left|200px]]<br /><applet load="1t6s" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1t6s, resolution 1.95&Aring;" />
 '''Crystal structure of a conserved hypothetical protein from Chlorobium tepidum'''<br />
 ==Overview==
-Structural maintenance of chromosome (SMC) proteins are essential in, chromosome condensation and interact with non-SMC proteins in eukaryotes, and with segregation and condensation proteins (ScpA and ScpB) in, prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405, encodes ScpB (ScpB_ChTe). The high resolution crystal structure of, ScpB_ChTe shows that the monomeric structure consists of two similarly, shaped globular domains composed of three helices sided by beta-strands [a, winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain, of Scc1, a functionally related eukaryotic ScpA homolog, as well as in, many DNA binding proteins.
+Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.
 ==About this Structure==
-T6S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls] with NO3 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA].
+T6S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls] with <scene name='pdbligand=NO3:'>NO3</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Chlorobium tepidum tls]]
 [[Category: Single protein]]
-[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]
+[[Category: BSGC, Berkeley Structural Genomics Center.]]
-[[Category: Kim, J.S.]]
+[[Category: Kim, J S.]]
 [[Category: Kim, R.]]
-[[Category: Kim, S.H.]]
+[[Category: Kim, S H.]]
-[[Category: Shin, D.H.]]
+[[Category: Shin, D H.]]
 [[Category: NO3]]
 [[Category: a winged helix-turn-helix]]
@@ Line 26: / Line 26: @@
 [[Category: structural genomics]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 01:46:01 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:10:28 2008''