MDM2: Difference between revisions
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MDM2 is an active inhibitor of the p53 anti-tumorgenesis protein. When MDM2 is atached p53 is unable to release transcription factors that code for apoptosis or halting of the cell cycle. The full cell signaling pathway is very complex, but MDM2 is usually activated by | MDM2 is an active inhibitor of the p53 anti-tumorgenesis protein. When MDM2 is atached p53 is unable to release transcription factors that code for apoptosis or halting of the cell cycle. The full cell signaling pathway is very complex, but MDM2 is usually activated by | ||
[[Image: | [[Image:Image:800px-Signal transduction v1.png]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:8875929</ref><references group="xtra"/> | <ref group="xtra">PMID:8875929</ref><references group="xtra"/> | ||
