3gis: Difference between revisions

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{{Seed}}
[[Image:3gis.png|left|200px]]
[[Image:3gis.png|left|200px]]


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{{STRUCTURE_3gis|  PDB=3gis  |  SCENE=  }}  
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===Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin===
===Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin===


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{{ABSTRACT_PUBMED_19656282}}


==Disease==
==About this Structure==
Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
[[3gis]] is a 9 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIS OCA].


==About this Structure==
==See Also==
3GIS is a 9 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIS OCA].
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:19656282</ref><references group="xtra"/>
<ref group="xtra">PMID:019656282</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Blood clotting]]
[[Category: Blood clotting]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Coagulation]]
[[Category: Coagulation]]
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[[Category: Kringle]]
[[Category: Kringle]]
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Pharmaceutical]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Protein-protein complex]]
[[Category: Protein-protein complex]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  7 13:29:01 2009''

Revision as of 22:02, 26 July 2012

File:3gis.png

Template:STRUCTURE 3gis

Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin

Template:ABSTRACT PUBMED 19656282

About this Structure

3gis is a 9 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Adams TE, Li W, Huntington JA. Molecular basis of thrombomodulin activation of slow thrombin. J Thromb Haemost. 2009 Oct;7(10):1688-95. Epub 2009 Jul 28. PMID:19656282 doi:10.1111/j.1538-7836.2009.03563.x

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