Highest impact structures: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Eran Hodis (talk | contribs)
Eric Martz (talk | contribs)
Line 27: Line 27:
* '''1987 - [[Major_Histocompatibility_Complex_Class_I | Major histocompatibility complex class I]]''': Created a paradigm shift in cellular immunology by explaining how MHC is involved in presenting hidden intracellular proteins to T lymphocytes. During the decade prior to this structure, this was a constantly debated but very murky mystery.
* '''1987 - [[Major_Histocompatibility_Complex_Class_I | Major histocompatibility complex class I]]''': Created a paradigm shift in cellular immunology by explaining how MHC is involved in presenting hidden intracellular proteins to T lymphocytes. During the decade prior to this structure, this was a constantly debated but very murky mystery.


* '''2000(?) - [[Ribosome]]''': This structure surprised almost everyone by showing that peptidyl transferase is a ribozyme, rather than a protein enzyme.
* '''2000 - [[Ribosome]]''': This structure surprised almost everyone by showing that peptidyl transferase is a ribozyme, rather than a protein enzyme. It won the [[Nobel_Prizes_for_3D_Molecular_Structure#Twenty-First_Century|2009 Nobel Prize in Chemistry]].


==Structures Saving The Most Lives==
==Structures Saving The Most Lives==