Intrinsically Disordered Protein: Difference between revisions
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== Examples of IUPs == | == Examples of IUPs == | ||
Examples cover a wide variety of cellular systems and it has been predicted that eukaryotes have more IUPs than other kingdoms <ref>PMID: 11700597</ref>. | Examples cover a wide variety of cellular systems and it has been predicted that eukaryotes have more IUPs than other kingdoms <ref>PMID: 11700597</ref>. Of course, there are no [[PDB codes]] for fully disordered proteins in isolation. However, there are some crystallographic results for IUP that fold in complex with another folded protein domain, such as [[1jsu]], [[1g3j]], and [[1oct]]<ref name="tompa2002" />. | ||
IUPs play roles in processes such as: | IUPs play roles in '''processes''' such as: | ||
* Cell signaling and cell cycle regulation, e.g. cyclin dependent kinase inhibitor p21Waf1/Cip1/Sdi1<ref>PMID: 8876165</ref> | * Cell signaling and cell cycle regulation, e.g. cyclin dependent kinase inhibitor p21Waf1/Cip1/Sdi1<ref>PMID: 8876165</ref> | ||
