3idp: Difference between revisions
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{{STRUCTURE_3idp| PDB=3idp | SCENE= }} | {{STRUCTURE_3idp| PDB=3idp | SCENE= }} | ||
===B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor=== | ===B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor=== | ||
{{ABSTRACT_PUBMED_19764794}} | {{ABSTRACT_PUBMED_19764794}} | ||
==About this Structure== | ==About this Structure== | ||
[[3idp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IDP OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019764794</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Epstein, L F.]] | [[Category: Epstein, L F.]] | ||
[[Category: Whittington, D A.]] | [[Category: Whittington, D A.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cardiomyopathy]] | [[Category: Cardiomyopathy]] | ||
[[Category: Dfg-out]] | [[Category: Dfg-out]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
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[[Category: Phorbol-ester binding]] | [[Category: Phorbol-ester binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 11:02, 13 March 2013
B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor
Template:ABSTRACT PUBMED 19764794
About this Structure
3idp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Smith AL, Demorin FF, Paras NA, Huang Q, Petkus JK, Doherty EM, Nixey T, Kim JL, Whittington DA, Epstein LF, Lee MR, Rose MJ, Babij C, Fernando M, Hess K, Le Q, Beltran P, Carnahan J. Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline. J Med Chem. 2009 Sep 18. PMID:19764794 doi:10.1021/jm901081g
