Intrinsically Disordered Protein: Difference between revisions
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Eric Martz (talk | contribs) →Protein disorder predictors: reorganized section |
Eric Martz (talk | contribs) →Prediction Servers: added WinDiso |
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=== Prediction Servers === | === Prediction Servers === | ||
* [http://bioinf.cs.ucl.ac.uk/disopred/ DISOPRED] | |||
* [http://bip.weizmann.ac.il/fldbin/findex/ FoldIndex]<ref name="foldindex" /> makes predictions based on the observation that IUPs occupy the low hydrophobicity/ high net-charge portion of charge-hydrophobicity phase space. (See Figure above.) | * [http://bip.weizmann.ac.il/fldbin/findex/ FoldIndex]<ref name="foldindex" /> makes predictions based on the observation that IUPs occupy the low hydrophobicity/ high net-charge portion of charge-hydrophobicity phase space. (See Figure above.) | ||
* [http:// | * [http://iupred.enzim.hu/ IUPred] | ||
* [http://www.pondr.com/ PONDR] | * [http://www.pondr.com/ PONDR] | ||
* [http:// | * [http://prodata.swmed.edu/Lab/Software.htm WinDiso]<ref>PMID: 17893360</ref> "is a linear, sequence- and alignment-based predictor of disordered/unfolded regions in proteins. It has the capability of adjusting for the increased tendency for disorder at protein termini. The simple weighted window-based algorithm and careful optimization technique make this a good predictor to use when trying to avoid bias toward special cases." (Quoted from the Grishin lab website.) | ||
''The above list is incomplete. Addition of other servers is welcome, and summaries of methods, pros and cons for each server would be useful.'' | ''The above list is incomplete. Addition of other servers is welcome, and summaries of methods, pros and cons for each server would be useful.'' | ||
