Kwon sandbox: Difference between revisions
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| id = | | id = | ||
| accessdate = 2008-10-14}}</ref> | | accessdate = 2008-10-14}}</ref> | ||
{{GNF_Protein_box | |||
| image = C-Myc-DNA complex.png | |||
| image_source = Structure of the c-Myc (red) in complex with Max (blue) and DNA ([[Protein_Data_Bank|PDB]] 1nkp). Both proteins are binding the major groove of the DNA by forming a fork-like structure. | |||
| PDB = {{PDB2|1nkp}} | |||
| Name = V-myc myelocytomatosis viral oncogene homolog (avian) | |||
| HGNCid = 7553 | |||
| Symbol = MYC | |||
| AltSymbols =; c-Myc | |||
| OMIM = 190080 | |||
| ECnumber = | |||
| Homologene = 31092 | |||
| MGIid = 97250 | |||
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} | |||
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005819 |text = spindle}} | |||
| Process = {{GNF_GO|id=GO:0001836 |text = release of cytochrome c from mitochondria}} {{GNF_GO|id=GO:0006309 |text = DNA fragmentation during apoptosis}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006879 |text = cellular iron ion homeostasis}} {{GNF_GO|id=GO:0006919 |text = caspase activation}} {{GNF_GO|id=GO:0007050 |text = cell cycle arrest}} {{GNF_GO|id=GO:0008284 |text = positive regulation of cell proliferation}} {{GNF_GO|id=GO:0008629 |text = induction of apoptosis by intracellular signals}} {{GNF_GO|id=GO:0008633 |text = activation of pro-apoptotic gene products}} {{GNF_GO|id=GO:0008634 |text = negative regulation of survival gene product activity}} {{GNF_GO|id=GO:0009314 |text = response to radiation}} {{GNF_GO|id=GO:0042981 |text = regulation of apoptosis}} | |||
| Hs_EntrezGene = 4609 | |||
| Hs_Ensembl = ENSG00000136997 | |||
| Hs_RefseqProtein = NP_002458 | |||
| Hs_RefseqmRNA = NM_002467 | |||
| Hs_GenLoc_db = hg18 | |||
| Hs_GenLoc_chr = | |||
| Hs_GenLoc_start = | |||
| Hs_GenLoc_end = | |||
| Hs_Uniprot = | |||
| Mm_EntrezGene = 17869 | |||
| Mm_Ensembl = ENSMUSG00000022346 | |||
| Mm_RefseqmRNA = NM_010849 | |||
| Mm_RefseqProtein = NP_034979 | |||
| Mm_GenLoc_db = mm8 | |||
| Mm_GenLoc_chr = 15 | |||
| Mm_GenLoc_start = 61815052 | |||
| Mm_GenLoc_end = 61820027 | |||
| Mm_Uniprot = O88594 | |||
}} | |||
<scene name='C-Myc/Custom/2'>TextToBeDisplayed</scene> | <scene name='C-Myc/Custom/2'>TextToBeDisplayed</scene> | ||