3ke1: Difference between revisions
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{{STRUCTURE_3ke1| PDB=3ke1 | SCENE= }} | {{STRUCTURE_3ke1| PDB=3ke1 | SCENE= }} | ||
===Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei in complex with a fragment-nucleoside fusion D000161829=== | ===Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei in complex with a fragment-nucleoside fusion D000161829=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/ISPF_BURPS ISPF_BURPS]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107] | |||
==About this Structure== | ==About this Structure== | ||
[[3ke1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KE1 OCA]. | |||
==See Also== | |||
*[[MECDP synthase|MECDP synthase]] | |||
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]] | [[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]] | ||
[[Category: Burkholderia pseudomallei]] | [[Category: Burkholderia pseudomallei]] | ||
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[[Category: Seattle structural genomics center for infectious disease]] | [[Category: Seattle structural genomics center for infectious disease]] | ||
[[Category: Ssgcid]] | [[Category: Ssgcid]] | ||
Revision as of 02:18, 4 April 2013
Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei in complex with a fragment-nucleoside fusion D000161829
Function
[ISPF_BURPS] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]
About this Structure
3ke1 is a 3 chain structure with sequence from Burkholderia pseudomallei. Full crystallographic information is available from OCA.
See Also
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
- Burkholderia pseudomallei
- SSGCID, Seattle Structural Genomics Center for Infectious Disease.
- D000161829
- Fbdd
- Fragment crystallography
- Fragment-based drug-design
- Isoprene biosynthesis
- Lyase
- Metal-binding
- Niaid
- Nucleoside analog
- Seattle structural genomics center for infectious disease
- Ssgcid
