3iit: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3iit.jpg|left|200px]]


The entry 3iit is ON HOLD until Aug 03 2011
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{{STRUCTURE_3iit|  PDB=3iit  |  SCENE=  }}


Authors: Suzuki, M.
===Factor XA in complex with a cis-1,2-diaminocyclohexane derivative===


Description: Factor XA in complex with a cis-1,2-diaminocyclohexane derivative


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:46:11 2009''
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{{ABSTRACT_PUBMED_19900814}}
 
==About this Structure==
3IIT is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IIT OCA].
 
==Reference==
<ref group="xtra">PMID:19900814</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Suzuki, M.]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation factor]]
[[Category: Calcium-binding]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disulfide bond]]
[[Category: Egf-like domain]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Plasma]]
[[Category: Protease]]
[[Category: Protein inhibitor complex]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug  4 09:06:20 2010''

Revision as of 04:59, 4 August 2010

File:3iit.jpg

Template:STRUCTURE 3iit

Factor XA in complex with a cis-1,2-diaminocyclohexane derivative

Template:ABSTRACT PUBMED 19900814

About this Structure

3IIT is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Yoshikawa K, Kobayashi S, Nakamoto Y, Haginoya N, Komoriya S, Yoshino T, Nagata T, Mochizuki A, Watanabe K, Suzuki M, Kanno H, Ohta T. Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties. Bioorg Med Chem. 2009 Dec 15;17(24):8221-33. Epub 2009 Oct 17. PMID:19900814 doi:10.1016/j.bmc.2009.10.024

Page seeded by OCA on Wed Aug 4 09:06:20 2010

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