3hxq: Difference between revisions

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{{Seed}}
{{Seed}}
[[Image:3hxq.jpg|left|200px]]
[[Image:3hxq.png|left|200px]]


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==About this Structure==
==About this Structure==
3HXQ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXQ OCA].  
3HXQ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXQ OCA].  


==Reference==
==Reference==
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[[Category: Vwf]]
[[Category: Vwf]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 20:08:26 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:54:28 2010''

Revision as of 12:54, 28 January 2010

File:3hxq.png

Template:STRUCTURE 3hxq

Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding

About this Structure

3HXQ is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Gilbert JC, DeFeo-Fraulini T, Hutabarat RM, Horvath CJ, Merlino PG, Marsh HN, Healy JM, Boufakhreddine S, Holohan TV, Schaub RG. First-in-human evaluation of anti von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers. Circulation. 2007 Dec 4;116(23):2678-86. Epub 2007 Nov 19. PMID:18025536 doi:10.1161/CIRCULATIONAHA.107.724864
  2. Diener JL, Daniel Lagasse HA, Duerschmied D, Merhi Y, Tanguay JF, Hutabarat R, Gilbert J, Wagner DD, Schaub R. Inhibition of von Willebrand factor-mediated platelet activation and thrombosis by the anti-von Willebrand factor A1-domain aptamer ARC1779. J Thromb Haemost. 2009 Jul;7(7):1155-62. Epub 2009 Apr 24. PMID:19422452 doi:10.1111/j.1538-7836.2009.03459.x

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