Human APP Intracellular Domain Complex with Fe65-PTB2: Difference between revisions
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There is an association between Aβ protein and Alzheimer’s disease because it is the major component found in plaques that are found in Alzheimer patients. Increased levels of Aβ protein are linked to a decrease of cognitive abilities which are observed in Alzheimer patients. <ref>PMID: 19374683</ref> | There is an association between Aβ protein and Alzheimer’s disease because it is the major component found in plaques that are found in Alzheimer patients. Increased levels of Aβ protein are linked to a decrease of cognitive abilities which are observed in Alzheimer patients. <ref>PMID: 19374683</ref> | ||
Besides neuritic plaques neurofibrillary tangles containing hyperphosphorylated tau protein are characteristic in the neuropathology of Alzheimer’s disease. Hyperphosphorylated tau protein and accumulated Aβ protein are considered to coexist. <ref>PMID: 19158417</ref> | |||
== References == | == References == | ||
<references /> | <references /> | ||
