1dpn: Difference between revisions
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New page: left|200px<br /><applet load="1dpn" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dpn, resolution 0.95Å" /> '''B-DODECAMER CGCGAA(T... |
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[[Image:1dpn.gif|left|200px]]<br /><applet load="1dpn" size=" | [[Image:1dpn.gif|left|200px]]<br /><applet load="1dpn" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1dpn, resolution 0.95Å" /> | caption="1dpn, resolution 0.95Å" /> | ||
'''B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE'''<br /> | '''B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE'''<br /> | ||
==Overview== | ==Overview== | ||
We have determined single crystal structures of an A-DNA decamer and a | We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition. | ||
==About this Structure== | ==About this Structure== | ||
1DPN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with MG as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | 1DPN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPN OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: An, H.]] | [[Category: An, H.]] | ||
[[Category: Cook, P | [[Category: Cook, P Dan.]] | ||
[[Category: Egli, M.]] | [[Category: Egli, M.]] | ||
[[Category: Joachimiak, A.]] | [[Category: Joachimiak, A.]] | ||
[[Category: Maier, M | [[Category: Maier, M A.]] | ||
[[Category: Manoharan, M.]] | [[Category: Manoharan, M.]] | ||
[[Category: Miller, R.]] | [[Category: Miller, R.]] | ||
| Line 23: | Line 23: | ||
[[Category: Teplova, M.]] | [[Category: Teplova, M.]] | ||
[[Category: Tereshko, V.]] | [[Category: Tereshko, V.]] | ||
[[Category: Weeks, C | [[Category: Weeks, C M.]] | ||
[[Category: MG]] | [[Category: MG]] | ||
[[Category: 0 | [[Category: 0 95 a resolution structure]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:19:04 2008'' | ||
