Reverse transcriptase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
mNo edit summary |
No edit summary |
||
| Line 5: | Line 5: | ||
==Structure== | ==Structure== | ||
This ''hand-like'' <scene name='Reverse_transcriptase/Chains/1'>heterodimer</scene> protein that has an usual length of 1000 residues(560 in Chain A and 440 for B), the third of them involved in alpha helical and almost a quarter in beta sheets <scene name='Reverse_transcriptase/Secondary/1'>secondary | This ''hand-like'' <scene name='Reverse_transcriptase/Chains/1'>heterodimer</scene> protein that has an usual length of 1000 residues(560 in Chain A and 440 for B), the third of them involved in alpha helical and almost a quarter in beta sheets <scene name='Reverse_transcriptase/Secondary/1'>α + β secondary structure domains</scene>; chain A with an usual weight of 65KDa contains the two actives sites and has the most conserved aminoacids, whereas chain B is around 50KDa and has more variable areas, result of drug resistant and function related evolution. [http://consurfdb.tau.ac.il/chain_selection.php?pdb_ID=1JLB] | ||
==Function== | ==Function== | ||
