3k10: Difference between revisions
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{{STRUCTURE_3k10| PDB=3k10 | SCENE= }} | {{STRUCTURE_3k10| PDB=3k10 | SCENE= }} | ||
===Crystal structure of telomere capping protein Stn1 from Saccharomyces cerevisiae=== | ===Crystal structure of telomere capping protein Stn1 from Saccharomyces cerevisiae=== | ||
{{ABSTRACT_PUBMED_19884503}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/STN1_YEAST STN1_YEAST]] Has a role in telomere length regulation and telomere end protection. Acts as an inhibitor of telomerase loading through its interaction with CDC13.<ref>PMID:9042864</ref><ref>PMID:11230140</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3k10]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K10 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019884503</ref><references group="xtra"/><references/> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Batey, R T.]] | [[Category: Batey, R T.]] | ||
| Line 35: | Line 22: | ||
[[Category: Telomere capping]] | [[Category: Telomere capping]] | ||
[[Category: Winged helix turn helix]] | [[Category: Winged helix turn helix]] | ||
Revision as of 09:41, 27 March 2013
Crystal structure of telomere capping protein Stn1 from Saccharomyces cerevisiae
Template:ABSTRACT PUBMED 19884503
Function
[STN1_YEAST] Has a role in telomere length regulation and telomere end protection. Acts as an inhibitor of telomerase loading through its interaction with CDC13.[1][2]
About this Structure
3k10 is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Gelinas AD, Paschini M, Reyes FE, Heroux A, Batey RT, Lundblad V, Wuttke DS. Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19298-303. Epub 2009 Nov 2. PMID:19884503
- ↑ Grandin N, Reed SI, Charbonneau M. Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. Genes Dev. 1997 Feb 15;11(4):512-27. PMID:9042864
- ↑ Grandin N, Damon C, Charbonneau M. Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13. EMBO J. 2001 Mar 1;20(5):1173-83. PMID:11230140 doi:10.1093/emboj/20.5.1173