Human beta two microglobulin: Difference between revisions
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=Structure of human beta two microglobulin= | =Structure of human beta two microglobulin= | ||
==Beta two microglubulin in human class I major histocompatibility complex (MHCb2m)== | ==Beta two microglubulin in human class I major histocompatibility complex (MHCb2m)== | ||
Human β2-Microglobulin is the non-covalently bound light chain of | Human β2-Microglobulin is the non-covalently bound light chain of the human class I | ||
< | major histocompatibility complex (MHC-I) | ||
major histocompatibility complex ( | <applet load='1duz' size='350' frame='true' align='right' caption='crystal structure of the human class | ||
I major histocompatibility complex (pdb 1DUZ)' /> | |||
its function is to ensure proper folding and cell-surface expression of MHC-1. | its function is to ensure proper folding and cell-surface expression of MHC-1. | ||
The natural turnover of MHC-I gives rise to the release of b2m into plasmatic fluids at ~0.1 | The natural turnover of MHC-I gives rise to the release of b2m into plasmatic fluids at ~0.1 | ||
