2x0v: Difference between revisions

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New page: '''Unreleased structure''' The entry 2x0v is ON HOLD Authors: Basse, N., Kaar, J.L., Joerger, A.C., Fersht, A.R. Description: STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(...
 
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'''Unreleased structure'''
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[[Image:2x0v.jpg|left|200px]]


The entry 2x0v is ON HOLD
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Authors: Basse, N., Kaar, J.L., Joerger, A.C., Fersht, A.R.
===STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE===


Description: STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-( trifluoromethyl)benzene-1,2-diamine


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 23 09:13:03 2009''
==About this Structure==
2X0V is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0V OCA].
 
==Reference==
<ref group="xtra">PMID:17015838</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Basse, N.]]
[[Category: Fersht, A R.]]
[[Category: Joerger, A C.]]
[[Category: Kaar, J L.]]
[[Category: Activator]]
[[Category: Apoptosis]]
[[Category: Cancer]]
[[Category: Cell cycle]]
[[Category: Host-virus interaction]]
[[Category: Li-fraumeni drug discovery]]
[[Category: Metal binding]]
[[Category: Protein stabilization]]
[[Category: Surface crevice]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Transcription regulation]]
[[Category: Tumor suppressor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:55:36 2010''

Revision as of 17:55, 27 January 2010

File:2x0v.jpg

Template:STRUCTURE 2x0v

STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE

About this Structure

2X0V is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

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