3gn2: Difference between revisions
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===Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)=== | ===Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)=== | ||
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The line below this paragraph, {{ABSTRACT_PUBMED_19527033}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 19527033 is the PubMed ID number. | |||
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{{ABSTRACT_PUBMED_19527033}} | |||
==About this Structure== | ==About this Structure== | ||
[[3gn2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GN2 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:019527033</ref><references group="xtra"/> | |||
[[Category: Trypanosoma brucei brucei]] | [[Category: Trypanosoma brucei brucei]] | ||
[[Category: Brenk, R.]] | [[Category: Brenk, R.]] | ||
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[[Category: Short chain dehydrogenase]] | [[Category: Short chain dehydrogenase]] | ||
[[Category: Trypanosoma brucei]] | [[Category: Trypanosoma brucei]] | ||
Revision as of 05:17, 7 September 2011
Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)
Template:ABSTRACT PUBMED 19527033
About this Structure
3gn2 is a 4 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.
Reference
- Mpamhanga CP, Spinks D, Tulloch LB, Shanks EJ, Robinson DA, Collie IT, Fairlamb AH, Wyatt PG, Frearson JA, Hunter WN, Gilbert IH, Brenk R. One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening. J Med Chem. 2009 Jun 15. PMID:19527033 doi:10.1021/jm900414x