3gn2: Difference between revisions

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[[Image:3gn2.png|left|200px]]
[[Image:3gn2.jpg|left|200px]]


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===Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)===
===Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)===


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{{ABSTRACT_PUBMED_19527033}}


==About this Structure==
==About this Structure==
3GN2 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GN2 OCA].  
[[3gn2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GN2 OCA].  
 
==Reference==
<ref group="xtra">PMID:019527033</ref><references group="xtra"/>
[[Category: Trypanosoma brucei brucei]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Brenk, R.]]
[[Category: Brenk, R.]]
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[[Category: Short chain dehydrogenase]]
[[Category: Short chain dehydrogenase]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 30 14:43:37 2009''

Revision as of 05:17, 7 September 2011

File:3gn2.png

Template:STRUCTURE 3gn2

Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)

Template:ABSTRACT PUBMED 19527033

About this Structure

3gn2 is a 4 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

Reference

  1. Mpamhanga CP, Spinks D, Tulloch LB, Shanks EJ, Robinson DA, Collie IT, Fairlamb AH, Wyatt PG, Frearson JA, Hunter WN, Gilbert IH, Brenk R. One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening. J Med Chem. 2009 Jun 15. PMID:19527033 doi:10.1021/jm900414x

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