User:Wayne Decatur/Haloarcula Large Ribosomal Subunit With Azithromycin: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
Wayne Decatur (talk | contribs)
Editor, widgeteditor
7,824 edits
mNo edit summary
Wayne Decatur (talk | contribs)
Editor, widgeteditor
7,824 edits
mNo edit summary
Line 1: Line 1:
Azithromycin is a 15-membered macrolide [http://en.wikipedia.org/wiki/Antibiotic antibiotic]. The structure of this clinically important antibiotic has been solved bound to the ''Haloarcula marismortui'' large ribosomal subunit revealing its mode of inhibiting protein synthesis<ref>PMID: 12150912</ref><ref>PMID: 15851032</ref>.
Azithromycin is a 15-membered macrolide [http://en.wikipedia.org/wiki/Antibiotic antibiotic]. The structure of this cliniclally important antibiotic has been solved bound to the ''Haloarcula marismortui'' large ribosomal subunit revealing its mode of inhibiting protein synthesis<ref>PMID: 12150912</ref><ref>PMID: 15851032</ref>.


The basic details of the [[User:Wayne Decatur/Haloarcula Large Ribosomal Subunit|''Haloarcula marismortui'' large ribosomal]] subunit are described in '''[[User:Wayne Decatur/Haloarcula Large Ribosomal Subunit|its own entry]]''' while the structure of azithromycin (zithromax) and its interaction with the [[ribosome]] are shown below on this page.
The basic details of the [[User:Wayne Decatur/Haloarcula Large Ribosomal Subunit|''Haloarcula marismortui'' large ribosomal]] subunit are described in '''[[User:Wayne Decatur/Haloarcula Large Ribosomal Subunit|its own entry]]'''.


==Mechanism of action==
==Mechanism of action==
Line 9: Line 9:
||
||
|<table width='410' align='left' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#eeeeee'><applet load='1m1kalphac.pdb.gz' size='410' frame='true' align='right' scene='User:Wayne_Decatur/Sandbox_Haloarcula_Large_Ribosomal_Subunit_With_Azithromycin/1m1kazo/2' /></td></tr><tr><td bgcolor='#eeeeee'><center>'''Azithromycin bound to the Large Ribosomal Subunit''' ([[1m1k]]), resolution 3.2&Aring; (<scene name='User:Wayne_Decatur/Sandbox_Haloarcula_Large_Ribosomal_Subunit_With_Azithromycin/1m1kazo/2>initial scene</scene>). <br>
|<table width='410' align='left' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#eeeeee'><applet load='1m1kalphac.pdb.gz' size='410' frame='true' align='right' scene='User:Wayne_Decatur/Sandbox_Haloarcula_Large_Ribosomal_Subunit_With_Azithromycin/1m1kazo/2' /></td></tr><tr><td bgcolor='#eeeeee'><center>'''Azithromycin bound to the Large Ribosomal Subunit''' ([[1m1k]]), resolution 3.2&Aring; (<scene name='User:Wayne_Decatur/Sandbox_Haloarcula_Large_Ribosomal_Subunit_With_Azithromycin/1m1kazo/2>initial scene</scene>). <br>
·· {{Link Toggle halolsuriborRNA}} ·· {{Link Toggle halolsu23SrRNA}} ·· {{Link Toggle halolsu5SrRNAb}} ··<br>·· {{Link Toggle 70SriboProtein}} ·· {{Link Toggle BlackWhiteBackground}}  ··</center></td></tr></table>
·· {{Link Toggle halolsuriborRNAb}} ·· {{Link Toggle halolsu23SrRNAb}} ·· {{Link Toggle halolsu5SrRNAb}} ··<br>·· {{Link Toggle 70SriboProtein}} ·· {{Link Toggle BlackWhiteBackground}}  ··</center></td></tr></table>
|}
|}


Retrieved from "https://proteopedia.org/User:Wayne_Decatur/Haloarcula_Large_Ribosomal_Subunit_With_Azithromycin"