3k41: Difference between revisions
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{{STRUCTURE_3k41| PDB=3k41 | SCENE= }} | {{STRUCTURE_3k41| PDB=3k41 | SCENE= }} | ||
===Crystal structure of sCD-MPR mutant E19Q/K137M bound to Man-6-P=== | ===Crystal structure of sCD-MPR mutant E19Q/K137M bound to Man-6-P=== | ||
{{ABSTRACT_PUBMED_19928875}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MPRD_BOVIN MPRD_BOVIN]] Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. | |||
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==About this Structure== | ==About this Structure== | ||
[[3k41]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K41 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019928875</ref><references group="xtra"/><references/> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Bohnsack, R N.]] | [[Category: Bohnsack, R N.]] | ||
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[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Protein transport]] | |||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Sugar binding]] | [[Category: Sugar binding]] | ||
[[Category: Sugar binding protein]] | |||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Transport]] | [[Category: Transport]] | ||