1opl: Difference between revisions

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{{Seed}}
[[Image:1opl.png|left|200px]]
[[Image:1opl.png|left|200px]]


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===Structural basis for the auto-inhibition of c-Abl tyrosine kinase===
===Structural basis for the auto-inhibition of c-Abl tyrosine kinase===


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{{ABSTRACT_PUBMED_12654251}}
{{ABSTRACT_PUBMED_12654251}}


==About this Structure==
==About this Structure==
1OPL is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Src Tyrosine Kinase''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_7 10.2210/rcsb_pdb/mom_2003_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OPL OCA].  
[[1opl]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Src Tyrosine Kinase''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_7 10.2210/rcsb_pdb/mom_2003_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OPL OCA].  
 
==See Also==
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:12654251</ref><references group="xtra"/>
<ref group="xtra">PMID:012654251</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Young, M A.]]
[[Category: Young, M A.]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 22:40:17 2010''

Revision as of 08:23, 27 July 2012

File:1opl.png


Drag the structure with the mouse to rotate
1opl, resolution 3.42Å (default scene)
Ligands: MYR, P16
Gene: Abl (Homo sapiens)
Activity: Transferase, with EC number and 2.7.10.2 2.7.10.1 and 2.7.10.2
Related: 1opj, 1opk
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Structural basis for the auto-inhibition of c-Abl tyrosine kinase

Template:ABSTRACT PUBMED 12654251

About this Structure

1opl is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. The July 2003 RCSB PDB Molecule of the Month feature on Src Tyrosine Kinase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2003_7. Full crystallographic information is available from OCA.

See Also

Reference

  1. Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Structural basis for the autoinhibition of c-Abl tyrosine kinase. Cell. 2003 Mar 21;112(6):859-71. PMID:12654251

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