3lj3: Difference between revisions
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New page: '''Unreleased structure''' The entry 3lj3 is ON HOLD Authors: Bard, J., Svenson, K. Description: PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor ''Page seeded by [http://... |
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===PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor=== | |||
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{{ABSTRACT_PUBMED_20188552}} | |||
==About this Structure== | |||
3LJ3 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJ3 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:20188552</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | |||
[[Category: Bard, J.]] | |||
[[Category: Svenson, K.]] | |||
[[Category: Atp-binding]] | |||
[[Category: Kinase]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Transferase]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 09:37:24 2010'' | |||
Revision as of 06:37, 14 April 2010
PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor
Template:ABSTRACT PUBMED 20188552
About this Structure
3LJ3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Tsou HR, MacEwan G, Birnberg G, Grosu G, Bursavich MG, Bard J, Brooijmans N, Toral-Barza L, Hollander I, Mansour TS, Ayral-Kaloustian S, Yu K. Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran- 3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). Bioorg Med Chem Lett. 2010 Apr 1;20(7):2321-5. Epub 2010 Feb 2. PMID:20188552 doi:10.1016/j.bmcl.2010.01.135
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