3l13: Difference between revisions

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{{Seed}}
[[Image:3l13.png|left|200px]]
[[Image:3l13.jpg|left|200px]]


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{{STRUCTURE_3l13|  PDB=3l13  |  SCENE=  }}  
{{STRUCTURE_3l13|  PDB=3l13  |  SCENE=  }}  


===Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors===
===Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors===


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{{ABSTRACT_PUBMED_20050669}}
{{ABSTRACT_PUBMED_20050669}}


==About this Structure==
==About this Structure==
3L13 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L13 OCA].  
[[3l13]] is a 1 chain structure of [[Phosphoinositide 3-Kinases]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L13 OCA].  
 
==See Also==
*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]


==Reference==
==Reference==
<ref group="xtra">PMID:20050669</ref><references group="xtra"/>
<ref group="xtra">PMID:020050669</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Pi3k-gamma p110 gamma]]
[[Category: Pi3k-gamma p110 gamma]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:29:34 2010''

Revision as of 15:02, 27 July 2012

File:3l13.png

Template:STRUCTURE 3l13

Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors

Template:ABSTRACT PUBMED 20050669

About this Structure

3l13 is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sutherlin DP, Sampath D, Berry M, Castanedo G, Chang Z, Chuckowree I, Dotson J, Folkes A, Friedman L, Goldsmith R, Heffron T, Lee L, Lesnick J, Lewis C, Mathieu S, Nonomiya J, Olivero A, Pang J, Prior WW, Salphati L, Sideris S, Tian Q, Tsui V, Wan NC, Wang S, Wiesmann C, Wong S, Zhu BY. Discovery of (Thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer. J Med Chem. 2010 Feb 11;53(3):1086-97. PMID:20050669 doi:10.1021/jm901284w

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