Retroviral Integrase: Difference between revisions
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[[Image:Strand Inhibition.jpg]] | [[Image:Strand Inhibition.jpg]] | ||
Above is a JMOL image of MK-0518 blocking the 3' end of the viral DNA from binding the active site. Notice the metal chelating oxygen atoms in MK-0518 interacting with the magnesium cations found in the active site. | |||
==Integrase Inhibitors== | ==Integrase Inhibitors== | ||