Retroviral Integrase: Difference between revisions

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[[Image:Strand Inhibition.jpg]]
[[Image:Strand Inhibition.jpg]]
Above is a JMOL image of MK-0518 blocking the 3' end of the viral DNA from binding the active site.  Notice the metal chelating oxygen atoms in MK-0518 interacting with the magnesium cations found in the active site.


==Integrase Inhibitors==  
==Integrase Inhibitors==