3hg3: Difference between revisions

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{{Seed}}
[[Image:3hg3.png|left|200px]]
[[Image:3hg3.png|left|200px]]


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{{STRUCTURE_3hg3|  PDB=3hg3  |  SCENE=  }}  
{{STRUCTURE_3hg3|  PDB=3hg3  |  SCENE=  }}  


===Human alpha-galactosidase catalytic mechanism 2. Substrate bound===
===Human alpha-galactosidase catalytic mechanism 2. Substrate bound===


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{{ABSTRACT_PUBMED_19940122}}
{{ABSTRACT_PUBMED_19940122}}


==Disease==
==About this Structure==
Known disease associated with this structure: Fabry disease OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300644 300644]], Fabry disease, cardiac variant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300644 300644]]
[[3hg3]] is a 2 chain structure of [[Galactosidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HG3 OCA].


==About this Structure==
==See Also==
3HG3 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HG3 OCA].
*[[Galactosidase|Galactosidase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19940122</ref><references group="xtra"/>
<ref group="xtra">PMID:019940122</ref><references group="xtra"/>
[[Category: Alpha-galactosidase]]
[[Category: Alpha-galactosidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Lysosomal enzyme]]
[[Category: Lysosomal enzyme]]
[[Category: Lysosome]]
[[Category: Lysosome]]
[[Category: Pharmaceutical]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 09:32:38 2010''

Revision as of 11:00, 26 July 2012

File:3hg3.png

Template:STRUCTURE 3hg3

Human alpha-galactosidase catalytic mechanism 2. Substrate bound

Template:ABSTRACT PUBMED 19940122

About this Structure

3hg3 is a 2 chain structure of Galactosidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Guce AI, Clark NE, Salgado EN, Ivanen DR, Kulminskaya AA, Brumer H 3rd, Garman SC. Catalytic mechanism of human alpha-galactosidase. J Biol Chem. 2010 Feb 5;285(6):3625-32. Epub 2009 Nov 25. PMID:19940122 doi:10.1074/jbc.M109.060145

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