413d: Difference between revisions

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[[Image:413d.jpg|left|200px]]<br /><applet load="413d" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:413d.jpg|left|200px]]<br /><applet load="413d" size="350" color="white" frame="true" align="right" spinBox="true"

caption="413d, resolution 1.800Å" />

'''A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)'''<br />

==Overview==

Here we demonstrate the presence of the A'-RNA conformation using the, single crystal structure of a tridecamer: r(UGAGCUUCGGCUC). The average, A'-RNA conformation deduced from X-ray fiber diffraction data had only, been available previously, but now the presence of the A'-RNA conformation, has been found in a single crystal structure for the first time., Statistical analysis showed that the A'-RNA conformation is, distinguishable from the A-RNA conformation in a plot of the major groove, width against the base pair inclination angle. The major groove of the, A'-RNA conformation is wide enough to accommodate a protein or peptide, while that of the A-RNA conformation is too narrow to do so. The presence, of the A'-RNA conformation is significant for protein-RNA interaction.

Here we demonstrate the presence of the A'-RNA conformation using the single crystal structure of a tridecamer: r(UGAGCUUCGGCUC). The average A'-RNA conformation deduced from X-ray fiber diffraction data had only been available previously, but now the presence of the A'-RNA conformation has been found in a single crystal structure for the first time. Statistical analysis showed that the A'-RNA conformation is distinguishable from the A-RNA conformation in a plot of the major groove width against the base pair inclination angle. The major groove of the A'-RNA conformation is wide enough to accommodate a protein or peptide while that of the A-RNA conformation is too narrow to do so. The presence of the A'-RNA conformation is significant for protein-RNA interaction.

==About this Structure==

413D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. This structure ~~superseeds~~ the now removed PDB entry 373D. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=413D OCA].

413D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. This structure supersedes the now removed PDB entry 373D. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=413D OCA].

==Reference==

Line 18:

[[Category: Tanaka, T.]]

[[Category: Tanaka, Y.]]

[[Category: Tomita, K.I.]]

[[Category: Tomita, K I.]]

[[Category: Uesugi, S.]]

[[Category: a'-rna]]

[[Category: double helix]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Sun Nov 25 08~~:56:~~50 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:12:01 2008''

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@@ Line 1: / Line 1: @@
-[[Image:413d.jpg|left|200px]]<br /><applet load="413d" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:413d.jpg|left|200px]]<br /><applet load="413d" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="413d, resolution 1.800&Aring;" />
 '''A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)'''<br />
 ==Overview==
-Here we demonstrate the presence of the A'-RNA conformation using the, single crystal structure of a tridecamer: r(UGAGCUUCGGCUC). The average, A'-RNA conformation deduced from X-ray fiber diffraction data had only, been available previously, but now the presence of the A'-RNA conformation, has been found in a single crystal structure for the first time., Statistical analysis showed that the A'-RNA conformation is, distinguishable from the A-RNA conformation in a plot of the major groove, width against the base pair inclination angle. The major groove of the, A'-RNA conformation is wide enough to accommodate a protein or peptide, while that of the A-RNA conformation is too narrow to do so. The presence, of the A'-RNA conformation is significant for protein-RNA interaction.
+Here we demonstrate the presence of the A'-RNA conformation using the single crystal structure of a tridecamer: r(UGAGCUUCGGCUC). The average A'-RNA conformation deduced from X-ray fiber diffraction data had only been available previously, but now the presence of the A'-RNA conformation has been found in a single crystal structure for the first time. Statistical analysis showed that the A'-RNA conformation is distinguishable from the A-RNA conformation in a plot of the major groove width against the base pair inclination angle. The major groove of the A'-RNA conformation is wide enough to accommodate a protein or peptide while that of the A-RNA conformation is too narrow to do so. The presence of the A'-RNA conformation is significant for protein-RNA interaction.
 ==About this Structure==
-D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. This structure superseeds the now removed PDB entry 373D. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=413D OCA].
+D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. This structure supersedes the now removed PDB entry 373D. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=413D OCA].
 ==Reference==
@@ Line 18: / Line 18: @@
 [[Category: Tanaka, T.]]
 [[Category: Tanaka, Y.]]
-[[Category: Tomita, K.I.]]
+[[Category: Tomita, K I.]]
 [[Category: Uesugi, S.]]
 [[Category: a'-rna]]
 [[Category: double helix]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 08:56:50 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:12:01 2008''