Phosphoglucoisomerase: Difference between revisions
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<applet load="1iat" size="300" color="white" frame="true" align="right" caption="Phosphoglucoisomerase" /> | <applet load="1iat" size="300" color="white" frame="true" align="right" caption="Phosphoglucoisomerase" /> | ||
'''Phosphoglucoisomerase''' (alternatively known as '''phosphoglucose isomerase''' or '''Glucose-6-phosphate isomerase''') are a group of enzymes of the isomerase family ([http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 EC 5.3.1.9]), so named for their main function in | '''Phosphoglucoisomerase''' (alternatively known as '''phosphoglucose isomerase''' or '''Glucose-6-phosphate isomerase''') are a group of enzymes of the isomerase family ([http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 EC 5.3.1.9]), so named for their main function in glycolysis and gluconeogenesis. In both these pathways phosphoglucose isomerase (PGI) is used to inter-convert glucose-6-phosphate and fructose 6-phosphate, reaction driven by the relative concentrations of these sugars in the cytoplasmic matrix of the cell. | ||
Phosphoglucoisomerase is also know for a list of activities outside the cells: | |||
* Neuroleukin (NLK)- nerve growth factor secreted by T cells, also used to stimulate the production of immunoglobulin. | |||
* Autocrine motility factor (AMF)- product of tumor cells, it promotes cell migration and viewed as a possible cause in cancer metastasis. | |||
* Maturation factor(MF) | |||
* Myofibril-bound serine protese inhibitor (MBSPI) | |||
=='''Structure'''== | =='''Structure'''== | ||
