Phosphoglycerate Kinase: Difference between revisions
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==Mechanism of Phosphoglycerate Kinase(PGK) Catalysis== | ==Mechanism of Phosphoglycerate Kinase(PGK) Catalysis== | ||
Phosphogylcerate kinase is a crucial enzyme of the glycolysis cycle. This cycle breaks down glucose into pyruvate while generating 2 NADH and 2 ATP molecules. Phosphogylcerate kinase is the seventh enzyme in the cycle which catalyzes the reaction of 1,3-Biphosphoglycerate and ADP to produce 3-Phosphoglycerate and <scene name='Shane_Harmon_Sandbox/Atp/1'> | Phosphogylcerate kinase is a crucial enzyme of the glycolysis cycle. This cycle breaks down glucose into pyruvate while generating 2 NADH and 2 ATP molecules. Phosphogylcerate kinase is the seventh enzyme in the cycle which catalyzes the reaction of 1,3-Biphosphoglycerate and ADP to produce <scene name='Shane_Harmon_Sandbox/Product/1'>3-Phosphoglycerate</scene> and <scene name='Shane_Harmon_Sandbox/Atp/1'>ATP</scene>. This method for ATP production is known as substrate level phosphorylation because it produces energy storing ATP molecules with out the use of oxygen, NADH, and an ATPase. The reaction is highly exergonic allowing it to be coupled with the GADPH reaction of the cycle.{{STRUCTURE_3cin | PDB=3PGK | SCENE= }} | ||