2i4q: Difference between revisions

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{{Seed}}
[[Image:2i4q.png|left|200px]]
[[Image:2i4q.png|left|200px]]


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{{STRUCTURE_2i4q|  PDB=2i4q  |  SCENE=  }}  
{{STRUCTURE_2i4q|  PDB=2i4q  |  SCENE=  }}  


===Human renin/PF02342674 complex===
===Human renin/PF02342674 complex===


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{{ABSTRACT_PUBMED_17574423}}
{{ABSTRACT_PUBMED_17574423}}


==Disease==
==About this Structure==
Known disease associated with this structure: Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]], Hyperproreninemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]]
[[2i4q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4Q OCA].


==About this Structure==
==See Also==
2I4Q is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4Q OCA].
*[[Renin|Renin]]


==Reference==
==Reference==
<ref group="xtra">PMID:17574423</ref><references group="xtra"/>
<ref group="xtra">PMID:017574423</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Renin]]
[[Category: Renin]]
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[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]
[[Category: Renin inhibitor]]
[[Category: Renin inhibitor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  3 14:37:40 2010''

Revision as of 09:10, 20 October 2012

File:2i4q.png

Template:STRUCTURE 2i4q

Human renin/PF02342674 complex

Template:ABSTRACT PUBMED 17574423

About this Structure

2i4q is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Powell NA, Ciske FL, Cai C, Holsworth DD, Mennen K, Van Huis CA, Jalaie M, Day J, Mastronardi M, McConnell P, Mochalkin I, Zhang E, Ryan MJ, Bryant J, Collard W, Ferreira S, Gu C, Collins R, Edmunds JJ. Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors. Bioorg Med Chem. 2007 Sep 1;15(17):5912-49. Epub 2007 Jun 2. PMID:17574423 doi:10.1016/j.bmc.2007.05.069

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