3jxc: Difference between revisions
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{{STRUCTURE_3jxc| PDB=3jxc | SCENE= }} | {{STRUCTURE_3jxc| PDB=3jxc | SCENE= }} | ||
===Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9T in the presence of Tl+=== | ===Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9T in the presence of Tl+=== | ||
{{ABSTRACT_PUBMED_20053356}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RPC2_BPP22 RPC2_BPP22]] This protein allows the phage to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein C2 to the OR and OL operators, preventing transcription of proteins necessary for lytic development. | |||
==About this Structure== | ==About this Structure== | ||
[[3jxc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p22 Enterobacteria phage p22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JXC OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020053356</ref><references group="xtra"/><references/> | ||
[[Category: Enterobacteria phage p22]] | [[Category: Enterobacteria phage p22]] | ||
[[Category: Koudelka, G B.]] | [[Category: Koudelka, G B.]] | ||
| Line 34: | Line 21: | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Transcription regulator]] | [[Category: Transcription regulator]] | ||
Revision as of 09:27, 27 March 2013
Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9T in the presence of Tl+
Template:ABSTRACT PUBMED 20053356
Function
[RPC2_BPP22] This protein allows the phage to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein C2 to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
About this Structure
3jxc is a 4 chain structure with sequence from Enterobacteria phage p22. Full crystallographic information is available from OCA.
Reference
- Watkins D, Mohan S, Koudelka GB, Williams LD. Sequence recognition of DNA by protein-induced conformational transitions. J Mol Biol. 2010 Mar 5;396(4):1145-64. Epub 2010 Jan 4. PMID:20053356 doi:10.1016/j.jmb.2009.12.050
